Stress induces major depressive disorder by a neutral sphingomyelinase 2-mediated accumulation of ceramide-enriched exosomes in the blood plasma

ABSTRACT: Major depressive disorder (MDD) is a very common, severe disease with a lifetime prevalence of ~ 10%. The pathogenesis of MDD is unknown and, unfortunately, therapy is often insufficient. We have previously reported that ceramide levels are increased in the blood plasma of patients with MD...

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Detalles Bibliográficos
Autores principales: Schumacher, Fabian, Carpinteiro, Alexander, Edwards, Michael J., Wilson, Gregory C., Keitsch, Simone, Soddemann, Matthias, Wilker, Barbara, Kleuser, Burkhard, Becker, Katrin Anne, Müller, Christian P., Kornhuber, Johannes, Gulbins, Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470690/
https://www.ncbi.nlm.nih.gov/pubmed/36045177
http://dx.doi.org/10.1007/s00109-022-02250-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470690/
https://www.ncbi.nlm.nih.gov/pubmed/36045177
http://dx.doi.org/10.1007/s00109-022-02250-y

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