Stress induces major depressive disorder by a neutral sphingomyelinase 2-mediated accumulation of ceramide-enriched exosomes in the blood plasma

ABSTRACT: Major depressive disorder (MDD) is a very common, severe disease with a lifetime prevalence of ~ 10%. The pathogenesis of MDD is unknown and, unfortunately, therapy is often insufficient. We have previously reported that ceramide levels are increased in the blood plasma of patients with MD...

Descripción completa

Detalles Bibliográficos
Autores principales: Schumacher, Fabian, Carpinteiro, Alexander, Edwards, Michael J., Wilson, Gregory C., Keitsch, Simone, Soddemann, Matthias, Wilker, Barbara, Kleuser, Burkhard, Becker, Katrin Anne, Müller, Christian P., Kornhuber, Johannes, Gulbins, Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470690/
https://www.ncbi.nlm.nih.gov/pubmed/36045177
http://dx.doi.org/10.1007/s00109-022-02250-y

Ejemplares similares

Ejemplares similares