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Interleukin-1 contributes to clonal expansion and progression of bone marrow fibrosis in JAK2V617F-induced myeloproliferative neoplasm

Chronic inflammation is frequently associated with myeloproliferative neoplasms (MPN), but the role of inflammation in the pathogenesis of MPN remains unclear. Expression of the proinflammatory cytokine interleukin-1 (IL-1) is elevated in patients with MPN as well as in Jak2V617F knock-in mice. Here...

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Detalles Bibliográficos
Autores principales:	Rahman, Mohammed Ferdous-Ur, Yang, Yue, Le, Bao T., Dutta, Avik, Posyniak, Julia, Faughnan, Patrick, Sayem, Mohammad A., Aguilera, Nadine S., Mohi, Golam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470702/ https://www.ncbi.nlm.nih.gov/pubmed/36100596 http://dx.doi.org/10.1038/s41467-022-32928-3

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