Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis

It is known that chondrocytes from joints with osteoarthritis (OA) exhibit high levels of DNA damage, but the degree to which chondrocytes accumulate DNA damage during “normal aging” has not been established. The goal of this study was to quantify the DNA damage present in chondrocytes obtained from...

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Detalles Bibliográficos
Autores principales: Copp, Michaela E., Chubinskaya, Susan, Bracey, Daniel N., Shine, Jacqueline, Sessions, Garrett, Loeser, Richard F., Diekman, Brian O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470893/
https://www.ncbi.nlm.nih.gov/pubmed/35996812
http://dx.doi.org/10.1111/acel.13698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470893/
https://www.ncbi.nlm.nih.gov/pubmed/35996812
http://dx.doi.org/10.1111/acel.13698

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