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Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis
It is known that chondrocytes from joints with osteoarthritis (OA) exhibit high levels of DNA damage, but the degree to which chondrocytes accumulate DNA damage during “normal aging” has not been established. The goal of this study was to quantify the DNA damage present in chondrocytes obtained from...
Autores principales: | Copp, Michaela E., Chubinskaya, Susan, Bracey, Daniel N., Shine, Jacqueline, Sessions, Garrett, Loeser, Richard F., Diekman, Brian O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470893/ https://www.ncbi.nlm.nih.gov/pubmed/35996812 http://dx.doi.org/10.1111/acel.13698 |
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