Intralipid administration in case of a severe venlafaxine overdose in a patient with previous gastric bypass surgery

This case describes a patient with a history of bariatric surgery who was admitted to our hospital with a severe venlafaxine intoxication. Due to the altered anatomy of the gastrointestinal tract, the use of oral activated charcoal and large volumes of laxatives to prevent further uptake of venlafax...

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Detalles Bibliográficos
Autores principales: de Wit, D., Franssen, E.J.F., Verstoep, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470933/
https://www.ncbi.nlm.nih.gov/pubmed/36119942
http://dx.doi.org/10.1016/j.toxrep.2022.05.008
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author de Wit, D.
Franssen, E.J.F.
Verstoep, N.
author_facet de Wit, D.
Franssen, E.J.F.
Verstoep, N.
author_sort de Wit, D.
collection PubMed
description This case describes a patient with a history of bariatric surgery who was admitted to our hospital with a severe venlafaxine intoxication. Due to the altered anatomy of the gastrointestinal tract, the use of oral activated charcoal and large volumes of laxatives to prevent further uptake of venlafaxine was hampered. This resulted in massive absorption and a severe serotonergic syndrome. The patient was successfully treated with intravenous lipid emulsion.
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spelling pubmed-94709332022-09-15 Intralipid administration in case of a severe venlafaxine overdose in a patient with previous gastric bypass surgery de Wit, D. Franssen, E.J.F. Verstoep, N. Toxicol Rep Regular Article This case describes a patient with a history of bariatric surgery who was admitted to our hospital with a severe venlafaxine intoxication. Due to the altered anatomy of the gastrointestinal tract, the use of oral activated charcoal and large volumes of laxatives to prevent further uptake of venlafaxine was hampered. This resulted in massive absorption and a severe serotonergic syndrome. The patient was successfully treated with intravenous lipid emulsion. Elsevier 2022-05-17 /pmc/articles/PMC9470933/ /pubmed/36119942 http://dx.doi.org/10.1016/j.toxrep.2022.05.008 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Regular Article
de Wit, D.
Franssen, E.J.F.
Verstoep, N.
Intralipid administration in case of a severe venlafaxine overdose in a patient with previous gastric bypass surgery
title Intralipid administration in case of a severe venlafaxine overdose in a patient with previous gastric bypass surgery
title_full Intralipid administration in case of a severe venlafaxine overdose in a patient with previous gastric bypass surgery
title_fullStr Intralipid administration in case of a severe venlafaxine overdose in a patient with previous gastric bypass surgery
title_full_unstemmed Intralipid administration in case of a severe venlafaxine overdose in a patient with previous gastric bypass surgery
title_short Intralipid administration in case of a severe venlafaxine overdose in a patient with previous gastric bypass surgery
title_sort intralipid administration in case of a severe venlafaxine overdose in a patient with previous gastric bypass surgery
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470933/
https://www.ncbi.nlm.nih.gov/pubmed/36119942
http://dx.doi.org/10.1016/j.toxrep.2022.05.008
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AT franssenejf intralipidadministrationincaseofaseverevenlafaxineoverdoseinapatientwithpreviousgastricbypasssurgery
AT verstoepn intralipidadministrationincaseofaseverevenlafaxineoverdoseinapatientwithpreviousgastricbypasssurgery

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