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Nontargeted metabolomics to characterize the effects of isotretinoin on skin metabolism in rabbit with acne

Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. This study aimed to explore the pathogenesis of acne and the therapeutic mechanism of isotretinoin from the metabolic perspective in coal tar-induced acne in rabbits. Methods: Ultra-high performance liquid chromat...

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Detalles Bibliográficos
Autores principales: Ou-Yang, Xiao-Liang, Zhang, Deng, Wang, Xiu-Ping, Yu, Si-Min, Xiao, Zhen, Li, Wei, Li, Chun-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470959/
https://www.ncbi.nlm.nih.gov/pubmed/36120319
http://dx.doi.org/10.3389/fphar.2022.963472