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Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program

INTRODUCTION: Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. OBJECTIVES: Aim of this study was to examine negative symptom structure in FES patients using the Positive...

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Detalles Bibliográficos
Autores principales: Pelizza, L., Leuci, E., Maestri, D., Quattrone, E., Paulillo, G., Pellegrini, P., Azzali, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470993/
http://dx.doi.org/10.1192/j.eurpsy.2021.448
Descripción
Sumario:INTRODUCTION: Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. OBJECTIVES: Aim of this study was to examine negative symptom structure in FES patients using the Positive and Negative Syndrome Scale (PANSS). METHODS: All 147 participants, aged 12–35 years, completed the PANSS and the Global Assessment of Functioning (GAF) scale. A principal component analysis with varimax rotation was performed to investigate PANSS negative symptom structure in the FES total sample. RESULTS: A 2-factor model (i.e. “Expressive Deficits” and “Asociality” dimensions) was identified. Only “Expressive Deficits” domain had a significant negative correlation with baseline GAF score. CONCLUSIONS: This bipartite solution seems to be adequate to describe the phenomenological variety of negative symptoms experienced by FES individuals at the point of entry in early intervention services. DISCLOSURE: No significant relationships.