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Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
INTRODUCTION: Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. OBJECTIVES: Aim of this study was to examine negative symptom structure in FES patients using the Positive...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470993/ http://dx.doi.org/10.1192/j.eurpsy.2021.448 |
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author | Pelizza, L. Leuci, E. Maestri, D. Quattrone, E. Paulillo, G. Pellegrini, P. Azzali, S. |
author_facet | Pelizza, L. Leuci, E. Maestri, D. Quattrone, E. Paulillo, G. Pellegrini, P. Azzali, S. |
author_sort | Pelizza, L. |
collection | PubMed |
description | INTRODUCTION: Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. OBJECTIVES: Aim of this study was to examine negative symptom structure in FES patients using the Positive and Negative Syndrome Scale (PANSS). METHODS: All 147 participants, aged 12–35 years, completed the PANSS and the Global Assessment of Functioning (GAF) scale. A principal component analysis with varimax rotation was performed to investigate PANSS negative symptom structure in the FES total sample. RESULTS: A 2-factor model (i.e. “Expressive Deficits” and “Asociality” dimensions) was identified. Only “Expressive Deficits” domain had a significant negative correlation with baseline GAF score. CONCLUSIONS: This bipartite solution seems to be adequate to describe the phenomenological variety of negative symptoms experienced by FES individuals at the point of entry in early intervention services. DISCLOSURE: No significant relationships. |
format | Online Article Text |
id | pubmed-9470993 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-94709932022-09-29 Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program Pelizza, L. Leuci, E. Maestri, D. Quattrone, E. Paulillo, G. Pellegrini, P. Azzali, S. Eur Psychiatry Abstract INTRODUCTION: Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. OBJECTIVES: Aim of this study was to examine negative symptom structure in FES patients using the Positive and Negative Syndrome Scale (PANSS). METHODS: All 147 participants, aged 12–35 years, completed the PANSS and the Global Assessment of Functioning (GAF) scale. A principal component analysis with varimax rotation was performed to investigate PANSS negative symptom structure in the FES total sample. RESULTS: A 2-factor model (i.e. “Expressive Deficits” and “Asociality” dimensions) was identified. Only “Expressive Deficits” domain had a significant negative correlation with baseline GAF score. CONCLUSIONS: This bipartite solution seems to be adequate to describe the phenomenological variety of negative symptoms experienced by FES individuals at the point of entry in early intervention services. DISCLOSURE: No significant relationships. Cambridge University Press 2021-08-13 /pmc/articles/PMC9470993/ http://dx.doi.org/10.1192/j.eurpsy.2021.448 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstract Pelizza, L. Leuci, E. Maestri, D. Quattrone, E. Paulillo, G. Pellegrini, P. Azzali, S. Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program |
title | Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program |
title_full | Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program |
title_fullStr | Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program |
title_full_unstemmed | Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program |
title_short | Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program |
title_sort | negative symptoms in first episode schizophrenia: results from the “parma early psychosis” program |
topic | Abstract |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470993/ http://dx.doi.org/10.1192/j.eurpsy.2021.448 |
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