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Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program

INTRODUCTION: Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. OBJECTIVES: Aim of this study was to examine negative symptom structure in FES patients using the Positive...

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Autores principales: Pelizza, L., Leuci, E., Maestri, D., Quattrone, E., Paulillo, G., Pellegrini, P., Azzali, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470993/
http://dx.doi.org/10.1192/j.eurpsy.2021.448
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author Pelizza, L.
Leuci, E.
Maestri, D.
Quattrone, E.
Paulillo, G.
Pellegrini, P.
Azzali, S.
author_facet Pelizza, L.
Leuci, E.
Maestri, D.
Quattrone, E.
Paulillo, G.
Pellegrini, P.
Azzali, S.
author_sort Pelizza, L.
collection PubMed
description INTRODUCTION: Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. OBJECTIVES: Aim of this study was to examine negative symptom structure in FES patients using the Positive and Negative Syndrome Scale (PANSS). METHODS: All 147 participants, aged 12–35 years, completed the PANSS and the Global Assessment of Functioning (GAF) scale. A principal component analysis with varimax rotation was performed to investigate PANSS negative symptom structure in the FES total sample. RESULTS: A 2-factor model (i.e. “Expressive Deficits” and “Asociality” dimensions) was identified. Only “Expressive Deficits” domain had a significant negative correlation with baseline GAF score. CONCLUSIONS: This bipartite solution seems to be adequate to describe the phenomenological variety of negative symptoms experienced by FES individuals at the point of entry in early intervention services. DISCLOSURE: No significant relationships.
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spelling pubmed-94709932022-09-29 Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program Pelizza, L. Leuci, E. Maestri, D. Quattrone, E. Paulillo, G. Pellegrini, P. Azzali, S. Eur Psychiatry Abstract INTRODUCTION: Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. OBJECTIVES: Aim of this study was to examine negative symptom structure in FES patients using the Positive and Negative Syndrome Scale (PANSS). METHODS: All 147 participants, aged 12–35 years, completed the PANSS and the Global Assessment of Functioning (GAF) scale. A principal component analysis with varimax rotation was performed to investigate PANSS negative symptom structure in the FES total sample. RESULTS: A 2-factor model (i.e. “Expressive Deficits” and “Asociality” dimensions) was identified. Only “Expressive Deficits” domain had a significant negative correlation with baseline GAF score. CONCLUSIONS: This bipartite solution seems to be adequate to describe the phenomenological variety of negative symptoms experienced by FES individuals at the point of entry in early intervention services. DISCLOSURE: No significant relationships. Cambridge University Press 2021-08-13 /pmc/articles/PMC9470993/ http://dx.doi.org/10.1192/j.eurpsy.2021.448 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Pelizza, L.
Leuci, E.
Maestri, D.
Quattrone, E.
Paulillo, G.
Pellegrini, P.
Azzali, S.
Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title_full Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title_fullStr Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title_full_unstemmed Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title_short Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program
title_sort negative symptoms in first episode schizophrenia: results from the “parma early psychosis” program
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470993/
http://dx.doi.org/10.1192/j.eurpsy.2021.448
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