The CHARTER-Ireland trial: can nebulised heparin reduce acute lung injury in patients with SARS-CoV-2 requiring advanced respiratory support in Ireland: a study protocol and statistical analysis plan for a randomised control trial

BACKGROUND: COVID-19 pneumonia is associated with the development of acute respiratory distress syndrome (ARDS) displaying some typical histological features. These include diffuse alveolar damage with extensive pulmonary coagulation activation. This results in fibrin deposition in the microvasculat...

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Detalles Bibliográficos
Autores principales: Sheehan, John Robert, Calpin, Padraig, Kernan, Maeve, Kelly, Claire, Casey, Siobhan, Murphy, Darragh, Alvarez-Iglesias, Alberto, Giacomini, Camilla, Cody, Catriona, Curley, Gerard, McGeary, Shane, Hanley, Ciara, McNicholas, Bairbre, van Haren, Frank, Laffey, John G., Cosgrave, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471050/
https://www.ncbi.nlm.nih.gov/pubmed/36104785
http://dx.doi.org/10.1186/s13063-022-06518-z

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