Cargando…
Effects of mutant lamins on nucleo-cytoskeletal coupling in Drosophila models of LMNA muscular dystrophy
The nuclei of multinucleated skeletal muscles experience substantial external force during development and muscle contraction. Protection from such forces is partly provided by lamins, intermediate filaments that form a scaffold lining the inner nuclear membrane. Lamins play a myriad of roles, inclu...
Autores principales: | Shaw, Nicholas M., Rios-Monterrosa, Jose L., Fedorchak, Gregory R., Ketterer, Margaret R., Coombs, Gary S., Lammerding, Jan, Wallrath, Lori L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471154/ https://www.ncbi.nlm.nih.gov/pubmed/36120560 http://dx.doi.org/10.3389/fcell.2022.934586 |
Ejemplares similares
-
Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins
por: Coombs, Gary S., et al.
Publicado: (2021) -
Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells
por: Earle, Ashley J., et al.
Publicado: (2019) -
Lamin A/C Assembly Defects in LMNA-Congenital Muscular Dystrophy Is Responsible for the Increased Severity of the Disease Compared with Emery–Dreifuss Muscular Dystrophy
por: Bertrand, Anne T., et al.
Publicado: (2020) -
Management of congenital muscular dystrophies related to defects in the LMNA gene
por: Quijano-Roy, Susana, et al.
Publicado: (2015) -
Characterization of cardiac involvement in children with LMNA-related muscular dystrophy
por: Cesar, Sergi, et al.
Publicado: (2023)