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Multiple brown tumors in primary hyperparathyroidism

Brown tumors are benign bone tumors that rarely complicate hyperparathyroidism, manifesting as fibrous and erosive lesions secondary to rapid and localized osteoclast turnover. These lesions are typical of primary hyperparathyroidism, but they are not often observed. We present the case of a 72-year...

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Autores principales: Ayadi, Chirihan, Lanjery, Safae, Andour, Hajar, Kamel, Farah, Qandili, Hamza El, Papys, Mendes, Jroundi, Laila, Laamrani, Fatima Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471336/
https://www.ncbi.nlm.nih.gov/pubmed/36120515
http://dx.doi.org/10.1016/j.radcr.2022.07.110
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author Ayadi, Chirihan
Lanjery, Safae
Andour, Hajar
Kamel, Farah
Qandili, Hamza El
Papys, Mendes
Jroundi, Laila
Laamrani, Fatima Zahra
author_facet Ayadi, Chirihan
Lanjery, Safae
Andour, Hajar
Kamel, Farah
Qandili, Hamza El
Papys, Mendes
Jroundi, Laila
Laamrani, Fatima Zahra
author_sort Ayadi, Chirihan
collection PubMed
description Brown tumors are benign bone tumors that rarely complicate hyperparathyroidism, manifesting as fibrous and erosive lesions secondary to rapid and localized osteoclast turnover. These lesions are typical of primary hyperparathyroidism, but they are not often observed. We present the case of a 72-year-old woman presenting with asthenia, bone pain, and hemiplegia. Biological analysis showed primary hyperparathyroidism, cervical ultrasound a right parathyroid adenoma that fixed on scintigraphy. When cross-sectional imaging was performed, it revealed multiple bone tumors of the axial and peripheral trunk with spinal cord compression which were diagnosed as brown tumors related to parathyroid adenoma. We illustrate through this case the importance of multidisciplinary imaging techniques before raising the diagnosis, especially in unusual pathologies such as brown tumors.
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spelling pubmed-94713362022-09-15 Multiple brown tumors in primary hyperparathyroidism Ayadi, Chirihan Lanjery, Safae Andour, Hajar Kamel, Farah Qandili, Hamza El Papys, Mendes Jroundi, Laila Laamrani, Fatima Zahra Radiol Case Rep Case Report Brown tumors are benign bone tumors that rarely complicate hyperparathyroidism, manifesting as fibrous and erosive lesions secondary to rapid and localized osteoclast turnover. These lesions are typical of primary hyperparathyroidism, but they are not often observed. We present the case of a 72-year-old woman presenting with asthenia, bone pain, and hemiplegia. Biological analysis showed primary hyperparathyroidism, cervical ultrasound a right parathyroid adenoma that fixed on scintigraphy. When cross-sectional imaging was performed, it revealed multiple bone tumors of the axial and peripheral trunk with spinal cord compression which were diagnosed as brown tumors related to parathyroid adenoma. We illustrate through this case the importance of multidisciplinary imaging techniques before raising the diagnosis, especially in unusual pathologies such as brown tumors. Elsevier 2022-09-09 /pmc/articles/PMC9471336/ /pubmed/36120515 http://dx.doi.org/10.1016/j.radcr.2022.07.110 Text en © 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ayadi, Chirihan
Lanjery, Safae
Andour, Hajar
Kamel, Farah
Qandili, Hamza El
Papys, Mendes
Jroundi, Laila
Laamrani, Fatima Zahra
Multiple brown tumors in primary hyperparathyroidism
title Multiple brown tumors in primary hyperparathyroidism
title_full Multiple brown tumors in primary hyperparathyroidism
title_fullStr Multiple brown tumors in primary hyperparathyroidism
title_full_unstemmed Multiple brown tumors in primary hyperparathyroidism
title_short Multiple brown tumors in primary hyperparathyroidism
title_sort multiple brown tumors in primary hyperparathyroidism
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471336/
https://www.ncbi.nlm.nih.gov/pubmed/36120515
http://dx.doi.org/10.1016/j.radcr.2022.07.110
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