Treatment of depression in the elderly with repetitive transcranial magnetic stimulation using theta-burst stimulation: Study protocol for a randomized, double-blind, controlled trial

INTRODUCTION: Transcranial magnetic stimulation (TMS) is a consolidated procedure for the treatment of depression, with several meta-analyses demonstrating its efficacy. Theta-burst stimulation (TBS) is a modification of TMS with similar efficacy and shorter session duration. The geriatric populatio...

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Detalles Bibliográficos
Autores principales: Valiengo, Leandro, Pinto, Bianca S., Marinho, Kalian A. P., Santos, Leonardo A., Tort, Luara C., Benatti, Rafael G., Teixeira, Bruna B., Miranda, Cristiane S., Cardeal, Henriette B., Suen, Paulo J. C., Loureiro, Julia C., Vaughan, Renata A. R., Dini Mattar, Roberta A. M. P. F., Lessa, Maíra, Oliveira, Pedro S., Silva, Valquíria A., Gattaz, Wagner Farid, Brunoni, André R., Forlenza, Orestes Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471379/
https://www.ncbi.nlm.nih.gov/pubmed/36118977
http://dx.doi.org/10.3389/fnhum.2022.941981
Descripción
Sumario:INTRODUCTION: Transcranial magnetic stimulation (TMS) is a consolidated procedure for the treatment of depression, with several meta-analyses demonstrating its efficacy. Theta-burst stimulation (TBS) is a modification of TMS with similar efficacy and shorter session duration. The geriatric population has many comorbidities and a high prevalence of depression, but few clinical trials are conducted specifically for this age group. TBS could be an option in this population, offering the advantages of few side effects and no pharmacological interactions. Therefore, our aim is to investigate the efficacy of TBS in geriatric depression. CLINICAL TRIAL REGISTRATION: [https://clinicaltrials.gov/ct2/], identifier [NCT04842929].

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