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Bipolar mania with psychosis vs without psychosis: A clinical characterization with indirect measures of severity

INTRODUCTION: The presence of psychotic symptoms is highest during acute episodes of bipolar mania. There is no evidence base regarding the implications of psychosis in the prognosis of bipolar disorder, despite common assumption that their occurrence reflects greater disease severity. OBJECTIVES: W...

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Autores principales: Andrade, F., Machado, A.S., Vieira, A., Silva, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471439/
http://dx.doi.org/10.1192/j.eurpsy.2021.247
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author Andrade, F.
Machado, A.S.
Vieira, A.
Silva, A.
author_facet Andrade, F.
Machado, A.S.
Vieira, A.
Silva, A.
author_sort Andrade, F.
collection PubMed
description INTRODUCTION: The presence of psychotic symptoms is highest during acute episodes of bipolar mania. There is no evidence base regarding the implications of psychosis in the prognosis of bipolar disorder, despite common assumption that their occurrence reflects greater disease severity. OBJECTIVES: We aim to compare sociodemographic and clinical characteristics of inpatients admitted for bipolar mania with and without psychotic features. METHODS: Retrospective observational study of inpatients admitted between January 1(st) 2017 and 31 October 2020 in a psychiatry inpatient unit of a tertiary hospital. Descriptive analysis of the results was performed using the SPSS software, version 26.0. RESULTS: Between 2017 and October 2020 there were 103 admissions due to mania bipolar I disorder, 53.4% (n=55) with psychotic symptoms. When compared with mania without psychosis, psychotic mania was associated to male gender (71.1% to 39.7%; c(2)(1, N = 103) = 10,06; p = 0.02) and younger age (t(103) = -2.43; p = 0.017). The proportion of compulsory admissions and average length of stay were similar between mania with psychosis and mania without psychosis. Also, having a manic bipolar episode with psychotic symptoms was not associated to being prescribed a long-acting injectable antipsychotic. CONCLUSIONS: The presence of psychotic symptoms in bipolar manic episodes were associated to male gender and younger age but not to indirect measures of illness severity. DISCLOSURE: No significant relationships.
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spelling pubmed-94714392022-09-29 Bipolar mania with psychosis vs without psychosis: A clinical characterization with indirect measures of severity Andrade, F. Machado, A.S. Vieira, A. Silva, A. Eur Psychiatry Abstract INTRODUCTION: The presence of psychotic symptoms is highest during acute episodes of bipolar mania. There is no evidence base regarding the implications of psychosis in the prognosis of bipolar disorder, despite common assumption that their occurrence reflects greater disease severity. OBJECTIVES: We aim to compare sociodemographic and clinical characteristics of inpatients admitted for bipolar mania with and without psychotic features. METHODS: Retrospective observational study of inpatients admitted between January 1(st) 2017 and 31 October 2020 in a psychiatry inpatient unit of a tertiary hospital. Descriptive analysis of the results was performed using the SPSS software, version 26.0. RESULTS: Between 2017 and October 2020 there were 103 admissions due to mania bipolar I disorder, 53.4% (n=55) with psychotic symptoms. When compared with mania without psychosis, psychotic mania was associated to male gender (71.1% to 39.7%; c(2)(1, N = 103) = 10,06; p = 0.02) and younger age (t(103) = -2.43; p = 0.017). The proportion of compulsory admissions and average length of stay were similar between mania with psychosis and mania without psychosis. Also, having a manic bipolar episode with psychotic symptoms was not associated to being prescribed a long-acting injectable antipsychotic. CONCLUSIONS: The presence of psychotic symptoms in bipolar manic episodes were associated to male gender and younger age but not to indirect measures of illness severity. DISCLOSURE: No significant relationships. Cambridge University Press 2021-08-13 /pmc/articles/PMC9471439/ http://dx.doi.org/10.1192/j.eurpsy.2021.247 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Andrade, F.
Machado, A.S.
Vieira, A.
Silva, A.
Bipolar mania with psychosis vs without psychosis: A clinical characterization with indirect measures of severity
title Bipolar mania with psychosis vs without psychosis: A clinical characterization with indirect measures of severity
title_full Bipolar mania with psychosis vs without psychosis: A clinical characterization with indirect measures of severity
title_fullStr Bipolar mania with psychosis vs without psychosis: A clinical characterization with indirect measures of severity
title_full_unstemmed Bipolar mania with psychosis vs without psychosis: A clinical characterization with indirect measures of severity
title_short Bipolar mania with psychosis vs without psychosis: A clinical characterization with indirect measures of severity
title_sort bipolar mania with psychosis vs without psychosis: a clinical characterization with indirect measures of severity
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471439/
http://dx.doi.org/10.1192/j.eurpsy.2021.247
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