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Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy

INTRODUCTION: Bipolar disorder (BD) is a serious and extremely recurrent illness frequently associated with cognitive and functional deterioration that poses many treatment challenges. However, over the years, with the evolution of more and more mood stabilizers and neuroleptics, there were controve...

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Autores principales: Bouali, W., Gniwa, R. Omezzine, Soussia, R. Ben, Mohamed, A. Hadj, Zarrouk, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471576/
http://dx.doi.org/10.1192/j.eurpsy.2021.527
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author Bouali, W.
Gniwa, R. Omezzine
Soussia, R. Ben
Mohamed, A. Hadj
Zarrouk, L.
author_facet Bouali, W.
Gniwa, R. Omezzine
Soussia, R. Ben
Mohamed, A. Hadj
Zarrouk, L.
author_sort Bouali, W.
collection PubMed
description INTRODUCTION: Bipolar disorder (BD) is a serious and extremely recurrent illness frequently associated with cognitive and functional deterioration that poses many treatment challenges. However, over the years, with the evolution of more and more mood stabilizers and neuroleptics, there were controversies surrounding the use of electroconvulsive therapy (ECT). OBJECTIVES: The present study was an attempt at studying the clinical profile of BD patients who receive ECT and to study its effectiveness. METHODS: Retrospective data were collected from all bipolar patients submitted to acute ECT treatment, between June 2015 and June 2016, at the Department of Psychiatry of the University Hospital of Mahdia, Tunisia. RESULTS: During the study period, among all the patients who received ECT, 47% were diagnosed to have bipolar disorder. ECT was administered most commonly for mania with psychotic symptoms, followed by severe depression with psychotic symptoms. Most of patients showed more than 65% response (based on reduction in the standardized rating scales) with ECT. Few patients (18.7%) reported some kind of side effects. CONCLUSIONS: ECT resulted very effective for all BD acute depressive and manic episodes not responding to conventional pharmacologic management.
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spelling pubmed-94715762022-09-29 Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy Bouali, W. Gniwa, R. Omezzine Soussia, R. Ben Mohamed, A. Hadj Zarrouk, L. Eur Psychiatry Abstract INTRODUCTION: Bipolar disorder (BD) is a serious and extremely recurrent illness frequently associated with cognitive and functional deterioration that poses many treatment challenges. However, over the years, with the evolution of more and more mood stabilizers and neuroleptics, there were controversies surrounding the use of electroconvulsive therapy (ECT). OBJECTIVES: The present study was an attempt at studying the clinical profile of BD patients who receive ECT and to study its effectiveness. METHODS: Retrospective data were collected from all bipolar patients submitted to acute ECT treatment, between June 2015 and June 2016, at the Department of Psychiatry of the University Hospital of Mahdia, Tunisia. RESULTS: During the study period, among all the patients who received ECT, 47% were diagnosed to have bipolar disorder. ECT was administered most commonly for mania with psychotic symptoms, followed by severe depression with psychotic symptoms. Most of patients showed more than 65% response (based on reduction in the standardized rating scales) with ECT. Few patients (18.7%) reported some kind of side effects. CONCLUSIONS: ECT resulted very effective for all BD acute depressive and manic episodes not responding to conventional pharmacologic management. Cambridge University Press 2021-08-13 /pmc/articles/PMC9471576/ http://dx.doi.org/10.1192/j.eurpsy.2021.527 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Bouali, W.
Gniwa, R. Omezzine
Soussia, R. Ben
Mohamed, A. Hadj
Zarrouk, L.
Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy
title Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy
title_full Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy
title_fullStr Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy
title_full_unstemmed Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy
title_short Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy
title_sort clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471576/
http://dx.doi.org/10.1192/j.eurpsy.2021.527
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