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Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study

INTRODUCTION: The burden of type 2 diabetes (T2DM) in China is increasing, with potential impacts on the health‐related quality of life (HRQoL) of those who develop the disease. Context‐specific assessment of HRQoL and its associated factors informs the development of contextually appropriate interv...

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Autores principales: Carter, Naomi, Li, Jialin, Xu, Miao, Li, Li, Fan, Xuelan, Zhu, Shuyan, Chahal, Pritpal, Chattopadhyay, Kaushik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471595/
https://www.ncbi.nlm.nih.gov/pubmed/35780497
http://dx.doi.org/10.1002/edm2.353
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author Carter, Naomi
Li, Jialin
Xu, Miao
Li, Li
Fan, Xuelan
Zhu, Shuyan
Chahal, Pritpal
Chattopadhyay, Kaushik
author_facet Carter, Naomi
Li, Jialin
Xu, Miao
Li, Li
Fan, Xuelan
Zhu, Shuyan
Chahal, Pritpal
Chattopadhyay, Kaushik
author_sort Carter, Naomi
collection PubMed
description INTRODUCTION: The burden of type 2 diabetes (T2DM) in China is increasing, with potential impacts on the health‐related quality of life (HRQoL) of those who develop the disease. Context‐specific assessment of HRQoL and its associated factors informs the development of contextually appropriate interventions to improve HRQoL. This study aimed to determine the HRQoL and its associated factors in people with T2DM at a tertiary care clinic in Ningbo, China. METHODS: A cross‐sectional survey was undertaken among 406 people with T2DM in 2020–21. The primary outcome was HRQoL measured using EQ VAS and EQ‐5D index from the EQ‐5D‐3L questionnaire. Multivariable regression analysis was used to determine the factors associated with HRQoL scores. RESULTS: The mean (± standard deviation) EQ VAS score was 68.7 (13.8). Median (interquartile range) EQ‐5D index was 1 (0.027). Prevalence of problems in HRQoL domains was as follows: pain/discomfort (15.7%), anxiety/depression (13.3%), mobility (5.4%), self‐care (3.5%) and managing usual activities (5.2%). The ≥60 years age group had a mean EQ VAS score 8.7 points higher (95% CI 3.4, 13.9; p < .001) than the 18–39 years age group. Those with T2DM >10 years had a mean EQ VAS score 8.6 points lower than those with a duration <1 year (−12.8, −4.4; p = .001). A T2DM duration >10 years was associated with a reduction in the EQ‐5D index of 0.029 (−0.041, −0.016; p < .001) compared with a duration <1 year. CONCLUSIONS: Depression/anxiety and pain/discomfort are important domains of reduced HRQoL for this population. A longer duration of T2DM is associated with reduced HRQoL scores, including both EQ VAS and EQ‐5D index. Increasing age may be counterintuitively associated with an increase in EQ VAS score in this population, potentially reflecting a ‘paradox of aging’ process. Future work should focus on developing, evaluating and implementing interventions to improve HRQoL in T2DM, such as strategies to manage pain and mental health conditions.
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spelling pubmed-94715952022-09-28 Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study Carter, Naomi Li, Jialin Xu, Miao Li, Li Fan, Xuelan Zhu, Shuyan Chahal, Pritpal Chattopadhyay, Kaushik Endocrinol Diabetes Metab Research Articles INTRODUCTION: The burden of type 2 diabetes (T2DM) in China is increasing, with potential impacts on the health‐related quality of life (HRQoL) of those who develop the disease. Context‐specific assessment of HRQoL and its associated factors informs the development of contextually appropriate interventions to improve HRQoL. This study aimed to determine the HRQoL and its associated factors in people with T2DM at a tertiary care clinic in Ningbo, China. METHODS: A cross‐sectional survey was undertaken among 406 people with T2DM in 2020–21. The primary outcome was HRQoL measured using EQ VAS and EQ‐5D index from the EQ‐5D‐3L questionnaire. Multivariable regression analysis was used to determine the factors associated with HRQoL scores. RESULTS: The mean (± standard deviation) EQ VAS score was 68.7 (13.8). Median (interquartile range) EQ‐5D index was 1 (0.027). Prevalence of problems in HRQoL domains was as follows: pain/discomfort (15.7%), anxiety/depression (13.3%), mobility (5.4%), self‐care (3.5%) and managing usual activities (5.2%). The ≥60 years age group had a mean EQ VAS score 8.7 points higher (95% CI 3.4, 13.9; p < .001) than the 18–39 years age group. Those with T2DM >10 years had a mean EQ VAS score 8.6 points lower than those with a duration <1 year (−12.8, −4.4; p = .001). A T2DM duration >10 years was associated with a reduction in the EQ‐5D index of 0.029 (−0.041, −0.016; p < .001) compared with a duration <1 year. CONCLUSIONS: Depression/anxiety and pain/discomfort are important domains of reduced HRQoL for this population. A longer duration of T2DM is associated with reduced HRQoL scores, including both EQ VAS and EQ‐5D index. Increasing age may be counterintuitively associated with an increase in EQ VAS score in this population, potentially reflecting a ‘paradox of aging’ process. Future work should focus on developing, evaluating and implementing interventions to improve HRQoL in T2DM, such as strategies to manage pain and mental health conditions. John Wiley and Sons Inc. 2022-07-03 /pmc/articles/PMC9471595/ /pubmed/35780497 http://dx.doi.org/10.1002/edm2.353 Text en © 2022 The Authors. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Carter, Naomi
Li, Jialin
Xu, Miao
Li, Li
Fan, Xuelan
Zhu, Shuyan
Chahal, Pritpal
Chattopadhyay, Kaushik
Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study
title Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study
title_full Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study
title_fullStr Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study
title_full_unstemmed Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study
title_short Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study
title_sort health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in ningbo, china: a cross‐sectional study
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471595/
https://www.ncbi.nlm.nih.gov/pubmed/35780497
http://dx.doi.org/10.1002/edm2.353
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