Cargando…
Social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis
INTRODUCTION: Social cognition has been associated with functional outcome in patients with first episode psychosis (FEP). Social cognition has also been associated with neurocognition and cognitive reserve. Although cognitive reserve, neurocognitive functioning, social cognition, and functional out...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471624/ http://dx.doi.org/10.1192/j.eurpsy.2021.436 |
_version_ | 1784789121595604992 |
---|---|
author | González-Ortega, I. Alberich-Mesa, S. Echeburúa, E. Bernardo, M. Cabrera, B. Amoretti, S. Lobo, A. Arango, C. Corripio, I. Vieta, E. De La Serna, E. Rodriguez-Jimenez, R. Segarra, R. López-Ilundain, J.M. Sánchez-Torres, A. Cuesta, M. González-Pinto, A. |
author_facet | González-Ortega, I. Alberich-Mesa, S. Echeburúa, E. Bernardo, M. Cabrera, B. Amoretti, S. Lobo, A. Arango, C. Corripio, I. Vieta, E. De La Serna, E. Rodriguez-Jimenez, R. Segarra, R. López-Ilundain, J.M. Sánchez-Torres, A. Cuesta, M. González-Pinto, A. |
author_sort | González-Ortega, I. |
collection | PubMed |
description | INTRODUCTION: Social cognition has been associated with functional outcome in patients with first episode psychosis (FEP). Social cognition has also been associated with neurocognition and cognitive reserve. Although cognitive reserve, neurocognitive functioning, social cognition, and functional outcome are related, the direction of their associations is not clear. OBJECTIVES: The aim of the study was to analyze the influence of social cognition as a mediator between cognitive reserve and cognitive domains on functioning in FEP both at baseline and at 2 years. METHODS: The sample of the study was composed of 282 FEP patients followed up for 2 years. To analyze whether social cognition mediates the influence of cognitive reserve and cognitive domains on functioning, a path analysis was performed. The statistical significance of any mediation effects was evaluated by bootstrap analysis. RESULTS: At baseline, as neither cognitive reserve nor the cognitive domains studied were related to functioning, the conditions for mediation were not satisfied. Nevertheless, at 2 years of follow-up, social cognition acted as a mediator between cognitive reserve and functioning. Likewise, social cognition was a mediator between verbal memory and functional outcome. The results of the bootstrap analysis confirmed these significant mediations (95% bootstrapped CI (−10.215 to −0.337) and (−4.731 to −0.605) respectively). CONCLUSIONS: Cognitive reserve and neurocognition are related to functioning, and social cognition mediates in this relationship. DISCLOSURE: This work was supported by the Carlos III Institute of Health and European Fund for Regional Development (PI08/1213, PI11/ 01977, PI14/01900, PI08/01026, PI11/02831, PI14/01621, PI08/1161, PI16/ 00359, PI16/01164, PI18/00805), the Basque Foundation for He |
format | Online Article Text |
id | pubmed-9471624 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-94716242022-09-29 Social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis González-Ortega, I. Alberich-Mesa, S. Echeburúa, E. Bernardo, M. Cabrera, B. Amoretti, S. Lobo, A. Arango, C. Corripio, I. Vieta, E. De La Serna, E. Rodriguez-Jimenez, R. Segarra, R. López-Ilundain, J.M. Sánchez-Torres, A. Cuesta, M. González-Pinto, A. Eur Psychiatry Abstract INTRODUCTION: Social cognition has been associated with functional outcome in patients with first episode psychosis (FEP). Social cognition has also been associated with neurocognition and cognitive reserve. Although cognitive reserve, neurocognitive functioning, social cognition, and functional outcome are related, the direction of their associations is not clear. OBJECTIVES: The aim of the study was to analyze the influence of social cognition as a mediator between cognitive reserve and cognitive domains on functioning in FEP both at baseline and at 2 years. METHODS: The sample of the study was composed of 282 FEP patients followed up for 2 years. To analyze whether social cognition mediates the influence of cognitive reserve and cognitive domains on functioning, a path analysis was performed. The statistical significance of any mediation effects was evaluated by bootstrap analysis. RESULTS: At baseline, as neither cognitive reserve nor the cognitive domains studied were related to functioning, the conditions for mediation were not satisfied. Nevertheless, at 2 years of follow-up, social cognition acted as a mediator between cognitive reserve and functioning. Likewise, social cognition was a mediator between verbal memory and functional outcome. The results of the bootstrap analysis confirmed these significant mediations (95% bootstrapped CI (−10.215 to −0.337) and (−4.731 to −0.605) respectively). CONCLUSIONS: Cognitive reserve and neurocognition are related to functioning, and social cognition mediates in this relationship. DISCLOSURE: This work was supported by the Carlos III Institute of Health and European Fund for Regional Development (PI08/1213, PI11/ 01977, PI14/01900, PI08/01026, PI11/02831, PI14/01621, PI08/1161, PI16/ 00359, PI16/01164, PI18/00805), the Basque Foundation for He Cambridge University Press 2021-08-13 /pmc/articles/PMC9471624/ http://dx.doi.org/10.1192/j.eurpsy.2021.436 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstract González-Ortega, I. Alberich-Mesa, S. Echeburúa, E. Bernardo, M. Cabrera, B. Amoretti, S. Lobo, A. Arango, C. Corripio, I. Vieta, E. De La Serna, E. Rodriguez-Jimenez, R. Segarra, R. López-Ilundain, J.M. Sánchez-Torres, A. Cuesta, M. González-Pinto, A. Social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis |
title | Social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis |
title_full | Social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis |
title_fullStr | Social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis |
title_full_unstemmed | Social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis |
title_short | Social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis |
title_sort | social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis |
topic | Abstract |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471624/ http://dx.doi.org/10.1192/j.eurpsy.2021.436 |
work_keys_str_mv | AT gonzalezortegai socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT alberichmesas socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT echeburuae socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT bernardom socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT cabrerab socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT amorettis socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT loboa socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT arangoc socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT corripioi socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT vietae socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT delasernae socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT rodriguezjimenezr socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT segarrar socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT lopezilundainjm socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT sancheztorresa socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT cuestam socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis AT gonzalezpintoa socialcognitionasamediatorbetweencognitivereserveandpsychosocialfunctioninginpatientswithfirstepisodepsychosis |