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Local and exhaustive study of transmission of detected psychopathological dimensions in family groups in the “albanova” area

INTRODUCTION: It is not known with certainty how different phenotypes are transmitted in groups of families divided into three generations. OBJECTIVES: Having meticulously searched for terms of psychopathogic lexicon that best translated the sterile categorical diagnosis, we obtained three dimension...

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Autores principales: Serritella, C., Russo, A., Rossi, G., Paolino, M., Baldascino, M., Vecchio, H. Del, Cimmino, M., Salvati, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471637/
http://dx.doi.org/10.1192/j.eurpsy.2021.858
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author Serritella, C.
Russo, A.
Rossi, G.
Paolino, M.
Baldascino, M.
Vecchio, H. Del
Cimmino, M.
Salvati, T.
author_facet Serritella, C.
Russo, A.
Rossi, G.
Paolino, M.
Baldascino, M.
Vecchio, H. Del
Cimmino, M.
Salvati, T.
author_sort Serritella, C.
collection PubMed
description INTRODUCTION: It is not known with certainty how different phenotypes are transmitted in groups of families divided into three generations. OBJECTIVES: Having meticulously searched for terms of psychopathogic lexicon that best translated the sterile categorical diagnosis, we obtained three dimensional groups for all six families in the three generations. METHODS: We calculated the frequencies and percentages of the three dimensional groups for the three generations of families based on sex. RESULTS: The chi-square TEST attests a p-value = 0.049, statistically significant for the dimensional group “A”. (Tab. 3) [Figure: see text] CONCLUSIONS: The genetics, and above all the epigenetics, of the phenotypes are periodically transmitted in group “A” and group “C” in the female and male sex. (Graphs 2.1.1 and 2.3.1) Different phenotypes indicate that the complexity of the interactions of the regulatory mechanisms of genes with the environment is extremely significant for the group with the most severe psychiatric pathology. [Figure: see text] [Figure: see text]
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spelling pubmed-94716372022-09-29 Local and exhaustive study of transmission of detected psychopathological dimensions in family groups in the “albanova” area Serritella, C. Russo, A. Rossi, G. Paolino, M. Baldascino, M. Vecchio, H. Del Cimmino, M. Salvati, T. Eur Psychiatry Abstract INTRODUCTION: It is not known with certainty how different phenotypes are transmitted in groups of families divided into three generations. OBJECTIVES: Having meticulously searched for terms of psychopathogic lexicon that best translated the sterile categorical diagnosis, we obtained three dimensional groups for all six families in the three generations. METHODS: We calculated the frequencies and percentages of the three dimensional groups for the three generations of families based on sex. RESULTS: The chi-square TEST attests a p-value = 0.049, statistically significant for the dimensional group “A”. (Tab. 3) [Figure: see text] CONCLUSIONS: The genetics, and above all the epigenetics, of the phenotypes are periodically transmitted in group “A” and group “C” in the female and male sex. (Graphs 2.1.1 and 2.3.1) Different phenotypes indicate that the complexity of the interactions of the regulatory mechanisms of genes with the environment is extremely significant for the group with the most severe psychiatric pathology. [Figure: see text] [Figure: see text] Cambridge University Press 2021-08-13 /pmc/articles/PMC9471637/ http://dx.doi.org/10.1192/j.eurpsy.2021.858 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Serritella, C.
Russo, A.
Rossi, G.
Paolino, M.
Baldascino, M.
Vecchio, H. Del
Cimmino, M.
Salvati, T.
Local and exhaustive study of transmission of detected psychopathological dimensions in family groups in the “albanova” area
title Local and exhaustive study of transmission of detected psychopathological dimensions in family groups in the “albanova” area
title_full Local and exhaustive study of transmission of detected psychopathological dimensions in family groups in the “albanova” area
title_fullStr Local and exhaustive study of transmission of detected psychopathological dimensions in family groups in the “albanova” area
title_full_unstemmed Local and exhaustive study of transmission of detected psychopathological dimensions in family groups in the “albanova” area
title_short Local and exhaustive study of transmission of detected psychopathological dimensions in family groups in the “albanova” area
title_sort local and exhaustive study of transmission of detected psychopathological dimensions in family groups in the “albanova” area
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471637/
http://dx.doi.org/10.1192/j.eurpsy.2021.858
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