Coordinated regulation of gene expression and microRNA changes in adipose tissue and circulating extracellular vesicles in response to pioglitazone treatment in humans with type 2 diabetes

Pioglitazone, a PPARγ agonist, is used to treat type 2 diabetes (T2D). PPARγ is highly expressed in adipose tissue (AT), however the effects of pioglitazone to improve insulin sensitivity are also evident in other tissues and PPARγ agonism has been shown to alter cancer derived extracellular vesicle...

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Detalles Bibliográficos
Autores principales: Nunez Lopez, Yury O., Casu, Anna, Kovacova, Zuzana, Petrilli, Alejandra M., Sideleva, Olga, Tharp, William G., Pratley, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471675/
https://www.ncbi.nlm.nih.gov/pubmed/36120427
http://dx.doi.org/10.3389/fendo.2022.955593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471675/
https://www.ncbi.nlm.nih.gov/pubmed/36120427
http://dx.doi.org/10.3389/fendo.2022.955593

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