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Quality of life in euthymic patients with bipolar disorder
INTRODUCTION: Patients with bipolar disorder (BD) frequently experience residual symptoms, problems in psychosocial functioning, cognitive impairment, and poor quality of life (QOL). OBJECTIVES: * To evaluate the QOL of euthymic patients with BD compared to healthy controls (HC). * To identify facto...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471793/ http://dx.doi.org/10.1192/j.eurpsy.2021.522 |
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author | Smaoui, N. Lajmi, I. Guermazi, A. Bouali, M. Maalej Omri, S. Feki, R. Zouari, L. Charfi, N. Thabet, J. Ben Maalej, M. |
author_facet | Smaoui, N. Lajmi, I. Guermazi, A. Bouali, M. Maalej Omri, S. Feki, R. Zouari, L. Charfi, N. Thabet, J. Ben Maalej, M. |
author_sort | Smaoui, N. |
collection | PubMed |
description | INTRODUCTION: Patients with bipolar disorder (BD) frequently experience residual symptoms, problems in psychosocial functioning, cognitive impairment, and poor quality of life (QOL). OBJECTIVES: * To evaluate the QOL of euthymic patients with BD compared to healthy controls (HC). * To identify factors associated with its deterioration. METHODS: This is a comparative and analytical study, conducted over 3 months, involving 30 euthymic patients with BD, followed up in the outpatient psychiatry department of Hedi Chaker University Hospital in Sfax (Tunisia). They were compared to 34 HC. General, clinical and therapeutic data were collected using a pre-established questionnaire. QOL was assessed with the «36 item Short-Form Health Survey» (SF-36). RESULTS: The mean ages of BD patients and HC were 44.17 years and 40.1 years, respectively. Compared with HC, patients with BD had decreased overall SF-36 scores (53.73 vs 73.78; p=0.000) and decreased physical and psychological subdomain scores (p=0.001; p=0.000). The study of the relationship between the dimensional average scores and different variables revealed correlations between; physical health problems and somatic disease (p=0.021) and unemployment (p=0.001), impaired general health and somatic disease (p=0.02) and psychotropic association (p=0.021), emotional health problems and psychiatric family history (p=0.023), pain and psychotropic association (p=0.031), and impaired global QOL and psychiatric family history (p=0.05). CONCLUSIONS: Our results confirm the impairment of the QOL of patients with BD even in euthymic periods. Many factors have been associated, including demographic and clinical variables. The improvement of QOL is to consider these factors in the management of these patients. |
format | Online Article Text |
id | pubmed-9471793 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-94717932022-09-29 Quality of life in euthymic patients with bipolar disorder Smaoui, N. Lajmi, I. Guermazi, A. Bouali, M. Maalej Omri, S. Feki, R. Zouari, L. Charfi, N. Thabet, J. Ben Maalej, M. Eur Psychiatry Abstract INTRODUCTION: Patients with bipolar disorder (BD) frequently experience residual symptoms, problems in psychosocial functioning, cognitive impairment, and poor quality of life (QOL). OBJECTIVES: * To evaluate the QOL of euthymic patients with BD compared to healthy controls (HC). * To identify factors associated with its deterioration. METHODS: This is a comparative and analytical study, conducted over 3 months, involving 30 euthymic patients with BD, followed up in the outpatient psychiatry department of Hedi Chaker University Hospital in Sfax (Tunisia). They were compared to 34 HC. General, clinical and therapeutic data were collected using a pre-established questionnaire. QOL was assessed with the «36 item Short-Form Health Survey» (SF-36). RESULTS: The mean ages of BD patients and HC were 44.17 years and 40.1 years, respectively. Compared with HC, patients with BD had decreased overall SF-36 scores (53.73 vs 73.78; p=0.000) and decreased physical and psychological subdomain scores (p=0.001; p=0.000). The study of the relationship between the dimensional average scores and different variables revealed correlations between; physical health problems and somatic disease (p=0.021) and unemployment (p=0.001), impaired general health and somatic disease (p=0.02) and psychotropic association (p=0.021), emotional health problems and psychiatric family history (p=0.023), pain and psychotropic association (p=0.031), and impaired global QOL and psychiatric family history (p=0.05). CONCLUSIONS: Our results confirm the impairment of the QOL of patients with BD even in euthymic periods. Many factors have been associated, including demographic and clinical variables. The improvement of QOL is to consider these factors in the management of these patients. Cambridge University Press 2021-08-13 /pmc/articles/PMC9471793/ http://dx.doi.org/10.1192/j.eurpsy.2021.522 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstract Smaoui, N. Lajmi, I. Guermazi, A. Bouali, M. Maalej Omri, S. Feki, R. Zouari, L. Charfi, N. Thabet, J. Ben Maalej, M. Quality of life in euthymic patients with bipolar disorder |
title | Quality of life in euthymic patients with bipolar disorder |
title_full | Quality of life in euthymic patients with bipolar disorder |
title_fullStr | Quality of life in euthymic patients with bipolar disorder |
title_full_unstemmed | Quality of life in euthymic patients with bipolar disorder |
title_short | Quality of life in euthymic patients with bipolar disorder |
title_sort | quality of life in euthymic patients with bipolar disorder |
topic | Abstract |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471793/ http://dx.doi.org/10.1192/j.eurpsy.2021.522 |
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