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Inflammatory perturbations in early life long-lastingly shape the transcriptome and TCR repertoire of the first wave of regulatory T cells

The first wave of Foxp3(+) regulatory T cells (Tregs) generated in neonates is critical for the life-long prevention of autoimmunity. Although it is widely accepted that neonates are highly susceptible to infections, the impact of neonatal infections on this first wave of Tregs is completely unknown...

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Detalles Bibliográficos
Autores principales:	Yang, Juhao, Zou, Mangge, Chu, Xiaojing, Floess, Stefan, Li, Yang, Delacher, Michael, Huehn, Jochen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471859/ https://www.ncbi.nlm.nih.gov/pubmed/36119090 http://dx.doi.org/10.3389/fimmu.2022.991671

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