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Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case
INTRODUCTION: SARS-CoV-2 is having an important direct impact, and also due to treatments used such as corticosteroids. Among its effects, we have focused on psychosis. OBJECTIVES: The objective of this paper is to study, from following case, incidence of steroid-induced psychosis in context of COVI...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471883/ http://dx.doi.org/10.1192/j.eurpsy.2021.834 |
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author | Villarroel, C. Martín Garcia, L. Carpio García, G. Belmonte Cutanda, J. Dominguez Revuelta, M. Sánchez Matsuura, J. Daza, M. Fernández-Torija García, E. |
author_facet | Villarroel, C. Martín Garcia, L. Carpio García, G. Belmonte Cutanda, J. Dominguez Revuelta, M. Sánchez Matsuura, J. Daza, M. Fernández-Torija García, E. |
author_sort | Villarroel, C. Martín |
collection | PubMed |
description | INTRODUCTION: SARS-CoV-2 is having an important direct impact, and also due to treatments used such as corticosteroids. Among its effects, we have focused on psychosis. OBJECTIVES: The objective of this paper is to study, from following case, incidence of steroid-induced psychosis in context of COVID-19. METHODS: A bibliographic search was performed from different database (Pubmed, TripDatabase) about psychiatric symptoms associated with use of corticosteroids during pandemic. 64-year-old woman with no psychiatric history, who is hospitalized for pneumonia secondary to SARS-Cov2 and treated with antibiotics, bronchodilators, and corticosteroids. At 4 days she began with injury and nihilistic delusions. The corticosteroids were progressively reduced, adding 2.5 mg Risperidone, resolving after ten days. RESULTS: Corticosteroids are currently being used to treat the systemic inflammatory response associated with COVID-19, but they can produce other effects such as psychiatric symptoms (3-6%): 75% affective (mainly hypomanic symptoms); and 25% psychotic. Steroid-induced psychosis are characterized by confusion, delusions, and hallucinations, and they usually begin 3-4 days after onset, and resolve within a week. They are associated especially with oral systemic steroids and high doses: 1.3% with 40mg of prednisone, and 18% with 80mg; increased this incidence due to the greater use that is being made to treat COVID-19 and the higher doses used in severe cases (up to 120 mg). CONCLUSIONS: To conclude, we need to know characteristics of these episodes in order to be able to prevent and treat them properly (minimum effective dose and less time), since they will probably occur more frequently at this time. |
format | Online Article Text |
id | pubmed-9471883 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-94718832022-09-29 Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case Villarroel, C. Martín Garcia, L. Carpio García, G. Belmonte Cutanda, J. Dominguez Revuelta, M. Sánchez Matsuura, J. Daza, M. Fernández-Torija García, E. Eur Psychiatry Abstract INTRODUCTION: SARS-CoV-2 is having an important direct impact, and also due to treatments used such as corticosteroids. Among its effects, we have focused on psychosis. OBJECTIVES: The objective of this paper is to study, from following case, incidence of steroid-induced psychosis in context of COVID-19. METHODS: A bibliographic search was performed from different database (Pubmed, TripDatabase) about psychiatric symptoms associated with use of corticosteroids during pandemic. 64-year-old woman with no psychiatric history, who is hospitalized for pneumonia secondary to SARS-Cov2 and treated with antibiotics, bronchodilators, and corticosteroids. At 4 days she began with injury and nihilistic delusions. The corticosteroids were progressively reduced, adding 2.5 mg Risperidone, resolving after ten days. RESULTS: Corticosteroids are currently being used to treat the systemic inflammatory response associated with COVID-19, but they can produce other effects such as psychiatric symptoms (3-6%): 75% affective (mainly hypomanic symptoms); and 25% psychotic. Steroid-induced psychosis are characterized by confusion, delusions, and hallucinations, and they usually begin 3-4 days after onset, and resolve within a week. They are associated especially with oral systemic steroids and high doses: 1.3% with 40mg of prednisone, and 18% with 80mg; increased this incidence due to the greater use that is being made to treat COVID-19 and the higher doses used in severe cases (up to 120 mg). CONCLUSIONS: To conclude, we need to know characteristics of these episodes in order to be able to prevent and treat them properly (minimum effective dose and less time), since they will probably occur more frequently at this time. Cambridge University Press 2021-08-13 /pmc/articles/PMC9471883/ http://dx.doi.org/10.1192/j.eurpsy.2021.834 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstract Villarroel, C. Martín Garcia, L. Carpio García, G. Belmonte Cutanda, J. Dominguez Revuelta, M. Sánchez Matsuura, J. Daza, M. Fernández-Torija García, E. Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case |
title | Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case |
title_full | Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case |
title_fullStr | Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case |
title_full_unstemmed | Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case |
title_short | Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case |
title_sort | steroid-induced psychosis in context a sars-cov-2 pandemic. about a case |
topic | Abstract |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471883/ http://dx.doi.org/10.1192/j.eurpsy.2021.834 |
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