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Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case

INTRODUCTION: SARS-CoV-2 is having an important direct impact, and also due to treatments used such as corticosteroids. Among its effects, we have focused on psychosis. OBJECTIVES: The objective of this paper is to study, from following case, incidence of steroid-induced psychosis in context of COVI...

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Autores principales: Villarroel, C. Martín, Garcia, L. Carpio, García, G. Belmonte, Cutanda, J. Dominguez, Revuelta, M. Sánchez, Matsuura, J., Daza, M. Fernández-Torija, García, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471883/
http://dx.doi.org/10.1192/j.eurpsy.2021.834
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author Villarroel, C. Martín
Garcia, L. Carpio
García, G. Belmonte
Cutanda, J. Dominguez
Revuelta, M. Sánchez
Matsuura, J.
Daza, M. Fernández-Torija
García, E.
author_facet Villarroel, C. Martín
Garcia, L. Carpio
García, G. Belmonte
Cutanda, J. Dominguez
Revuelta, M. Sánchez
Matsuura, J.
Daza, M. Fernández-Torija
García, E.
author_sort Villarroel, C. Martín
collection PubMed
description INTRODUCTION: SARS-CoV-2 is having an important direct impact, and also due to treatments used such as corticosteroids. Among its effects, we have focused on psychosis. OBJECTIVES: The objective of this paper is to study, from following case, incidence of steroid-induced psychosis in context of COVID-19. METHODS: A bibliographic search was performed from different database (Pubmed, TripDatabase) about psychiatric symptoms associated with use of corticosteroids during pandemic. 64-year-old woman with no psychiatric history, who is hospitalized for pneumonia secondary to SARS-Cov2 and treated with antibiotics, bronchodilators, and corticosteroids. At 4 days she began with injury and nihilistic delusions. The corticosteroids were progressively reduced, adding 2.5 mg Risperidone, resolving after ten days. RESULTS: Corticosteroids are currently being used to treat the systemic inflammatory response associated with COVID-19, but they can produce other effects such as psychiatric symptoms (3-6%): 75% affective (mainly hypomanic symptoms); and 25% psychotic. Steroid-induced psychosis are characterized by confusion, delusions, and hallucinations, and they usually begin 3-4 days after onset, and resolve within a week. They are associated especially with oral systemic steroids and high doses: 1.3% with 40mg of prednisone, and 18% with 80mg; increased this incidence due to the greater use that is being made to treat COVID-19 and the higher doses used in severe cases (up to 120 mg). CONCLUSIONS: To conclude, we need to know characteristics of these episodes in order to be able to prevent and treat them properly (minimum effective dose and less time), since they will probably occur more frequently at this time.
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spelling pubmed-94718832022-09-29 Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case Villarroel, C. Martín Garcia, L. Carpio García, G. Belmonte Cutanda, J. Dominguez Revuelta, M. Sánchez Matsuura, J. Daza, M. Fernández-Torija García, E. Eur Psychiatry Abstract INTRODUCTION: SARS-CoV-2 is having an important direct impact, and also due to treatments used such as corticosteroids. Among its effects, we have focused on psychosis. OBJECTIVES: The objective of this paper is to study, from following case, incidence of steroid-induced psychosis in context of COVID-19. METHODS: A bibliographic search was performed from different database (Pubmed, TripDatabase) about psychiatric symptoms associated with use of corticosteroids during pandemic. 64-year-old woman with no psychiatric history, who is hospitalized for pneumonia secondary to SARS-Cov2 and treated with antibiotics, bronchodilators, and corticosteroids. At 4 days she began with injury and nihilistic delusions. The corticosteroids were progressively reduced, adding 2.5 mg Risperidone, resolving after ten days. RESULTS: Corticosteroids are currently being used to treat the systemic inflammatory response associated with COVID-19, but they can produce other effects such as psychiatric symptoms (3-6%): 75% affective (mainly hypomanic symptoms); and 25% psychotic. Steroid-induced psychosis are characterized by confusion, delusions, and hallucinations, and they usually begin 3-4 days after onset, and resolve within a week. They are associated especially with oral systemic steroids and high doses: 1.3% with 40mg of prednisone, and 18% with 80mg; increased this incidence due to the greater use that is being made to treat COVID-19 and the higher doses used in severe cases (up to 120 mg). CONCLUSIONS: To conclude, we need to know characteristics of these episodes in order to be able to prevent and treat them properly (minimum effective dose and less time), since they will probably occur more frequently at this time. Cambridge University Press 2021-08-13 /pmc/articles/PMC9471883/ http://dx.doi.org/10.1192/j.eurpsy.2021.834 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Villarroel, C. Martín
Garcia, L. Carpio
García, G. Belmonte
Cutanda, J. Dominguez
Revuelta, M. Sánchez
Matsuura, J.
Daza, M. Fernández-Torija
García, E.
Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case
title Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case
title_full Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case
title_fullStr Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case
title_full_unstemmed Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case
title_short Steroid-induced psychosis in context a SARS-CoV-2 pandemic. about a case
title_sort steroid-induced psychosis in context a sars-cov-2 pandemic. about a case
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471883/
http://dx.doi.org/10.1192/j.eurpsy.2021.834
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