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A systematic review and meta-analysis of BRCA1/2 mutation for predicting the effect of platinum-based chemotherapy in triple-negative breast cancer

INTRODUCTION: Platinum-based chemotherapy (PBC) remains the mainstay of treatments for triple-negative breast cancer (TNBC). TNBC is a heterogeneous group, the issue of whether BRCA1/2 mutation carriers have a particular sensitivity to platinum agents is inconclusive. We conducted a meta-analysis to...

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Detalles Bibliográficos
Autores principales: Jia, Xiaomeng, Wang, Kainan, Xu, Lingzhi, Li, Ning, Zhao, Zuowei, Li, Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471971/
https://www.ncbi.nlm.nih.gov/pubmed/36096071
http://dx.doi.org/10.1016/j.breast.2022.08.012

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