Structural studies of the coiled-coil domain of TRIM75 reveal a tetramer architecture facilitating its E3 ligase complex

Protein ubiquitination plays a vital role in controlling the degradation of intracellular proteins and in regulating cell signaling pathways. Functionally, E3 ubiquitin ligases control the transfer of ubiquitin to the target substrates. As a major family of ubiquitin E3 ligases, the structural assem...

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Detalles Bibliográficos
Autores principales: Lou, Xiaohua, Ma, Binbin, Zhuang, Yuan, Xiao, Xiang, Minze, Laurie J., Xing, Junji, Zhang, Zhiqiang, Li, Xian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471973/
https://www.ncbi.nlm.nih.gov/pubmed/36147661
http://dx.doi.org/10.1016/j.csbj.2022.08.069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471973/
https://www.ncbi.nlm.nih.gov/pubmed/36147661
http://dx.doi.org/10.1016/j.csbj.2022.08.069

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