Distinct gene expression by expanded clones of quiescent memory CD4(+) T cells harboring intact latent HIV-1 proviruses

Antiretroviral therapy controls, but does not cure, HIV-1 infection due to a reservoir of rare CD4(+) T cells harboring latent proviruses. Little is known about the transcriptional program of latent cells. Here, we report a strategy to enrich clones of latent cells carrying intact, replication-compe...

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Detalles Bibliográficos
Autores principales: Weymar, Georg H.J., Bar-On, Yotam, Oliveira, Thiago Y., Gaebler, Christian, Ramos, Victor, Hartweger, Harald, Breton, Gaëlle, Caskey, Marina, Cohn, Lillian B., Jankovic, Mila, Nussenzweig, Michel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471989/
https://www.ncbi.nlm.nih.gov/pubmed/36070690
http://dx.doi.org/10.1016/j.celrep.2022.111311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9471989/
https://www.ncbi.nlm.nih.gov/pubmed/36070690
http://dx.doi.org/10.1016/j.celrep.2022.111311

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