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Epidemiological characteristics of extrapulmonary tuberculosis patients with or without pulmonary tuberculosis
Our study aimed to investigate the epidemiology of extrapulmonary tuberculosis (EPTB) and analyse the epidemiological characteristics of EPTB patients with or without pulmonary tuberculosis (PTB). EPTB cases admitted in our hospital from January 2015 to December 2020 were included. Uni- and multi-va...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cambridge University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472030/ https://www.ncbi.nlm.nih.gov/pubmed/35904011 http://dx.doi.org/10.1017/S0950268822001236 |
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author | Fang, Yong Zhou, Qinqi Li, Lin Zhou, Yiming Sha, Wei |
author_facet | Fang, Yong Zhou, Qinqi Li, Lin Zhou, Yiming Sha, Wei |
author_sort | Fang, Yong |
collection | PubMed |
description | Our study aimed to investigate the epidemiology of extrapulmonary tuberculosis (EPTB) and analyse the epidemiological characteristics of EPTB patients with or without pulmonary tuberculosis (PTB). EPTB cases admitted in our hospital from January 2015 to December 2020 were included. Uni- and multi-variable logistic regression analysis was carried out to identify risk factors and prognostic factors of concomitant EPTB and PTB or exclusively EPTB. A total of 3488 EPTB patients were reviewed, including 2086 patients with concurrent PTB and EPTB, and 1402 patients with exclusively EPTB. Logistic regression analysis showed that age >60 years (OR = 1.674, 95% CI = 1.438–1.949, P < 0.001) and female (OR = 1.325, 95% CI = 1.155–1.520, P < 0.001) were risk factors of exclusively EPTB, while co-morbidities (OR = 0.676, 95% CI = 0.492–0.929, P = 0.016) and severe symptoms (OR = 0.613, 95% CI = 0.405–0.929, P = 0.021) were risk factors for concurrence of EPTB and PTB. Age >60 years was an independent prognostic factor in EPTB patients with or without PTB (HR = 11.059, 95%CI = 5.097–23.999, P < 0.001; HR = 23.994, 95%CI = 3.093–186.151, P = 0.0020). Female gender was an independent prognostic factor in patients with concurrent PTB and EPTB (HR = 23.994, 95%CI = 3.093–186.151, P = 0.002). Our study disclosed the differential epidemiological characteristics of EPTB patients with or without PTB in China. |
format | Online Article Text |
id | pubmed-9472030 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-94720302022-09-15 Epidemiological characteristics of extrapulmonary tuberculosis patients with or without pulmonary tuberculosis Fang, Yong Zhou, Qinqi Li, Lin Zhou, Yiming Sha, Wei Epidemiol Infect Original Paper Our study aimed to investigate the epidemiology of extrapulmonary tuberculosis (EPTB) and analyse the epidemiological characteristics of EPTB patients with or without pulmonary tuberculosis (PTB). EPTB cases admitted in our hospital from January 2015 to December 2020 were included. Uni- and multi-variable logistic regression analysis was carried out to identify risk factors and prognostic factors of concomitant EPTB and PTB or exclusively EPTB. A total of 3488 EPTB patients were reviewed, including 2086 patients with concurrent PTB and EPTB, and 1402 patients with exclusively EPTB. Logistic regression analysis showed that age >60 years (OR = 1.674, 95% CI = 1.438–1.949, P < 0.001) and female (OR = 1.325, 95% CI = 1.155–1.520, P < 0.001) were risk factors of exclusively EPTB, while co-morbidities (OR = 0.676, 95% CI = 0.492–0.929, P = 0.016) and severe symptoms (OR = 0.613, 95% CI = 0.405–0.929, P = 0.021) were risk factors for concurrence of EPTB and PTB. Age >60 years was an independent prognostic factor in EPTB patients with or without PTB (HR = 11.059, 95%CI = 5.097–23.999, P < 0.001; HR = 23.994, 95%CI = 3.093–186.151, P = 0.0020). Female gender was an independent prognostic factor in patients with concurrent PTB and EPTB (HR = 23.994, 95%CI = 3.093–186.151, P = 0.002). Our study disclosed the differential epidemiological characteristics of EPTB patients with or without PTB in China. Cambridge University Press 2022-07-29 /pmc/articles/PMC9472030/ /pubmed/35904011 http://dx.doi.org/10.1017/S0950268822001236 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided that no alterations are made and the original article is properly cited. The written permission of Cambridge University Press must be obtained prior to any commercial use and/or adaptation of the article. |
spellingShingle | Original Paper Fang, Yong Zhou, Qinqi Li, Lin Zhou, Yiming Sha, Wei Epidemiological characteristics of extrapulmonary tuberculosis patients with or without pulmonary tuberculosis |
title | Epidemiological characteristics of extrapulmonary tuberculosis patients with or without pulmonary tuberculosis |
title_full | Epidemiological characteristics of extrapulmonary tuberculosis patients with or without pulmonary tuberculosis |
title_fullStr | Epidemiological characteristics of extrapulmonary tuberculosis patients with or without pulmonary tuberculosis |
title_full_unstemmed | Epidemiological characteristics of extrapulmonary tuberculosis patients with or without pulmonary tuberculosis |
title_short | Epidemiological characteristics of extrapulmonary tuberculosis patients with or without pulmonary tuberculosis |
title_sort | epidemiological characteristics of extrapulmonary tuberculosis patients with or without pulmonary tuberculosis |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472030/ https://www.ncbi.nlm.nih.gov/pubmed/35904011 http://dx.doi.org/10.1017/S0950268822001236 |
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