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An Efficient Method for Deidentifying Protected Health Information in Chinese Electronic Health Records: Algorithm Development and Validation

BACKGROUND: With the popularization of electronic health records in China, the utilization of digitalized data has great potential for the development of real-world medical research. However, the data usually contains a great deal of protected health information and the direct usage of this data may...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Li, Yong, Yang, Liang, Li, Simin, Li, Linfeng, Zhao, Zehan, Long, Shaopei, Wang, Fei, Wang, Hongqian, Li, Ying, Wang, Chengliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472063/
https://www.ncbi.nlm.nih.gov/pubmed/36040774
http://dx.doi.org/10.2196/38154
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author Wang, Peng
Li, Yong
Yang, Liang
Li, Simin
Li, Linfeng
Zhao, Zehan
Long, Shaopei
Wang, Fei
Wang, Hongqian
Li, Ying
Wang, Chengliang
author_facet Wang, Peng
Li, Yong
Yang, Liang
Li, Simin
Li, Linfeng
Zhao, Zehan
Long, Shaopei
Wang, Fei
Wang, Hongqian
Li, Ying
Wang, Chengliang
author_sort Wang, Peng
collection PubMed
description BACKGROUND: With the popularization of electronic health records in China, the utilization of digitalized data has great potential for the development of real-world medical research. However, the data usually contains a great deal of protected health information and the direct usage of this data may cause privacy issues. The task of deidentifying protected health information in electronic health records can be regarded as a named entity recognition problem. Existing rule-based, machine learning–based, or deep learning–based methods have been proposed to solve this problem. However, these methods still face the difficulties of insufficient Chinese electronic health record data and the complex features of the Chinese language. OBJECTIVE: This paper proposes a method to overcome the difficulties of overfitting and a lack of training data for deep neural networks to enable Chinese protected health information deidentification. METHODS: We propose a new model that merges TinyBERT (bidirectional encoder representations from transformers) as a text feature extraction module and the conditional random field method as a prediction module for deidentifying protected health information in Chinese medical electronic health records. In addition, a hybrid data augmentation method that integrates a sentence generation strategy and a mention-replacement strategy is proposed for overcoming insufficient Chinese electronic health records. RESULTS: We compare our method with 5 baseline methods that utilize different BERT models as their feature extraction modules. Experimental results on the Chinese electronic health records that we collected demonstrate that our method had better performance (microprecision: 98.7%, microrecall: 99.13%, and micro-F1 score: 98.91%) and higher efficiency (40% faster) than all the BERT-based baseline methods. CONCLUSIONS: Compared to baseline methods, the efficiency advantage of TinyBERT on our proposed augmented data set was kept while the performance improved for the task of Chinese protected health information deidentification.
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spelling pubmed-94720632022-09-15 An Efficient Method for Deidentifying Protected Health Information in Chinese Electronic Health Records: Algorithm Development and Validation Wang, Peng Li, Yong Yang, Liang Li, Simin Li, Linfeng Zhao, Zehan Long, Shaopei Wang, Fei Wang, Hongqian Li, Ying Wang, Chengliang JMIR Med Inform Original Paper BACKGROUND: With the popularization of electronic health records in China, the utilization of digitalized data has great potential for the development of real-world medical research. However, the data usually contains a great deal of protected health information and the direct usage of this data may cause privacy issues. The task of deidentifying protected health information in electronic health records can be regarded as a named entity recognition problem. Existing rule-based, machine learning–based, or deep learning–based methods have been proposed to solve this problem. However, these methods still face the difficulties of insufficient Chinese electronic health record data and the complex features of the Chinese language. OBJECTIVE: This paper proposes a method to overcome the difficulties of overfitting and a lack of training data for deep neural networks to enable Chinese protected health information deidentification. METHODS: We propose a new model that merges TinyBERT (bidirectional encoder representations from transformers) as a text feature extraction module and the conditional random field method as a prediction module for deidentifying protected health information in Chinese medical electronic health records. In addition, a hybrid data augmentation method that integrates a sentence generation strategy and a mention-replacement strategy is proposed for overcoming insufficient Chinese electronic health records. RESULTS: We compare our method with 5 baseline methods that utilize different BERT models as their feature extraction modules. Experimental results on the Chinese electronic health records that we collected demonstrate that our method had better performance (microprecision: 98.7%, microrecall: 99.13%, and micro-F1 score: 98.91%) and higher efficiency (40% faster) than all the BERT-based baseline methods. CONCLUSIONS: Compared to baseline methods, the efficiency advantage of TinyBERT on our proposed augmented data set was kept while the performance improved for the task of Chinese protected health information deidentification. JMIR Publications 2022-08-30 /pmc/articles/PMC9472063/ /pubmed/36040774 http://dx.doi.org/10.2196/38154 Text en ©Peng Wang, Yong Li, Liang Yang, Simin Li, Linfeng Li, Zehan Zhao, Shaopei Long, Fei Wang, Hongqian Wang, Ying Li, Chengliang Wang. Originally published in JMIR Medical Informatics (https://medinform.jmir.org), 30.08.2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Medical Informatics, is properly cited. The complete bibliographic information, a link to the original publication on https://medinform.jmir.org/, as well as this copyright and license information must be included.
spellingShingle Original Paper
Wang, Peng
Li, Yong
Yang, Liang
Li, Simin
Li, Linfeng
Zhao, Zehan
Long, Shaopei
Wang, Fei
Wang, Hongqian
Li, Ying
Wang, Chengliang
An Efficient Method for Deidentifying Protected Health Information in Chinese Electronic Health Records: Algorithm Development and Validation
title An Efficient Method for Deidentifying Protected Health Information in Chinese Electronic Health Records: Algorithm Development and Validation
title_full An Efficient Method for Deidentifying Protected Health Information in Chinese Electronic Health Records: Algorithm Development and Validation
title_fullStr An Efficient Method for Deidentifying Protected Health Information in Chinese Electronic Health Records: Algorithm Development and Validation
title_full_unstemmed An Efficient Method for Deidentifying Protected Health Information in Chinese Electronic Health Records: Algorithm Development and Validation
title_short An Efficient Method for Deidentifying Protected Health Information in Chinese Electronic Health Records: Algorithm Development and Validation
title_sort efficient method for deidentifying protected health information in chinese electronic health records: algorithm development and validation
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472063/
https://www.ncbi.nlm.nih.gov/pubmed/36040774
http://dx.doi.org/10.2196/38154
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