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Rational incorporation of any unnatural amino acid into proteins by machine learning on existing experimental proofs

The unnatural amino acid (UAA) incorporation technique through genetic code expansion has been extensively used in protein engineering for the last two decades. Mutations into UAAs offer more dimensions to tune protein structures and functions. However, the huge library of optional UAAs and various...

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Detalles Bibliográficos
Autores principales: Zhang, Haoran, Zheng, Zhetao, Dong, Liangzhen, Shi, Ningning, Yang, Yuelin, Chen, Hongmin, Shen, Yuxuan, Xia, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472073/
https://www.ncbi.nlm.nih.gov/pubmed/36147660
http://dx.doi.org/10.1016/j.csbj.2022.08.063

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