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Rational incorporation of any unnatural amino acid into proteins by machine learning on existing experimental proofs
The unnatural amino acid (UAA) incorporation technique through genetic code expansion has been extensively used in protein engineering for the last two decades. Mutations into UAAs offer more dimensions to tune protein structures and functions. However, the huge library of optional UAAs and various...
Autores principales: | Zhang, Haoran, Zheng, Zhetao, Dong, Liangzhen, Shi, Ningning, Yang, Yuelin, Chen, Hongmin, Shen, Yuxuan, Xia, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472073/ https://www.ncbi.nlm.nih.gov/pubmed/36147660 http://dx.doi.org/10.1016/j.csbj.2022.08.063 |
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