Human CIDEC transgene improves lipid metabolism and protects against high-fat diet–induced glucose intolerance in mice

Cell death–inducing DNA fragmentation factor-like effector C (CIDEC) expression in adipose tissue positively correlates with insulin sensitivity in obese humans. Further, E186X, a single-nucleotide CIDEC variant is associated with lipodystrophy, hypertriglyceridemia, and insulin resistance. To estab...

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Detalles Bibliográficos
Autores principales: Gupta, Abhishek, Balakrishnan, Bijinu, Karki, Shakun, Slayton, Mark, Jash, Sukanta, Banerjee, Sayani, Grahn, Tan Hooi Min, Jambunathan, Srikarthika, Disney, Sarah, Hussein, Hebaallaha, Kong, Dong, Lowell, Bradford B., Natarajan, Purushothaman, Reddy, Umesh K., Gokce, Noyan, Sharma, Vishva M., Puri, Vishwajeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472082/
https://www.ncbi.nlm.nih.gov/pubmed/35963433
http://dx.doi.org/10.1016/j.jbc.2022.102347

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