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Renal malakoplakia with invasion of the liver and diaphragm: a patient case and literature review

Renal malakoplakia, a seldom seen chronic inflammatory condition, continues to elude medical, surgical, radiological and pathological specialists due to its mimicry of other renal pathologies and low incidence. The variable clinical manifestations and non-specific radiological findings of malakoplak...

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Autores principales: Grunhut, Joel, Oroz, Ricardo, Brown, Shimron, Nazarian-Rostami, Roozbeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472137/
https://www.ncbi.nlm.nih.gov/pubmed/36100289
http://dx.doi.org/10.1136/bcr-2022-251254
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author Grunhut, Joel
Oroz, Ricardo
Brown, Shimron
Nazarian-Rostami, Roozbeh
author_facet Grunhut, Joel
Oroz, Ricardo
Brown, Shimron
Nazarian-Rostami, Roozbeh
author_sort Grunhut, Joel
collection PubMed
description Renal malakoplakia, a seldom seen chronic inflammatory condition, continues to elude medical, surgical, radiological and pathological specialists due to its mimicry of other renal pathologies and low incidence. The variable clinical manifestations and non-specific radiological findings of malakoplakia can be misleading, and ultimately require a pathological diagnosis. A literature review reveals an extremely low prevalence of renal malakoplakia, a handful of invasive renal malakoplakia cases and no reports of liver and diaphragmatic invasion. We present a case of a renal mass with liver and diaphragmatic invasion in a 59-year-old woman that deceived clinicians and radiologists until a pathological diagnosis of renal malakoplakia was performed. This case highlights the need of awareness for malakoplakia in the differential diagnosis for renal invasive and non-invasive masses. The need to await a surgical biopsy and pathological diagnosis is critical to ensure a correct diagnosis and avoid unnecessary surgery of the kidney.
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spelling pubmed-94721372022-09-15 Renal malakoplakia with invasion of the liver and diaphragm: a patient case and literature review Grunhut, Joel Oroz, Ricardo Brown, Shimron Nazarian-Rostami, Roozbeh BMJ Case Rep Case Reports: Rare disease Renal malakoplakia, a seldom seen chronic inflammatory condition, continues to elude medical, surgical, radiological and pathological specialists due to its mimicry of other renal pathologies and low incidence. The variable clinical manifestations and non-specific radiological findings of malakoplakia can be misleading, and ultimately require a pathological diagnosis. A literature review reveals an extremely low prevalence of renal malakoplakia, a handful of invasive renal malakoplakia cases and no reports of liver and diaphragmatic invasion. We present a case of a renal mass with liver and diaphragmatic invasion in a 59-year-old woman that deceived clinicians and radiologists until a pathological diagnosis of renal malakoplakia was performed. This case highlights the need of awareness for malakoplakia in the differential diagnosis for renal invasive and non-invasive masses. The need to await a surgical biopsy and pathological diagnosis is critical to ensure a correct diagnosis and avoid unnecessary surgery of the kidney. BMJ Publishing Group 2022-09-13 /pmc/articles/PMC9472137/ /pubmed/36100289 http://dx.doi.org/10.1136/bcr-2022-251254 Text en © BMJ Publishing Group Limited 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Case Reports: Rare disease
Grunhut, Joel
Oroz, Ricardo
Brown, Shimron
Nazarian-Rostami, Roozbeh
Renal malakoplakia with invasion of the liver and diaphragm: a patient case and literature review
title Renal malakoplakia with invasion of the liver and diaphragm: a patient case and literature review
title_full Renal malakoplakia with invasion of the liver and diaphragm: a patient case and literature review
title_fullStr Renal malakoplakia with invasion of the liver and diaphragm: a patient case and literature review
title_full_unstemmed Renal malakoplakia with invasion of the liver and diaphragm: a patient case and literature review
title_short Renal malakoplakia with invasion of the liver and diaphragm: a patient case and literature review
title_sort renal malakoplakia with invasion of the liver and diaphragm: a patient case and literature review
topic Case Reports: Rare disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472137/
https://www.ncbi.nlm.nih.gov/pubmed/36100289
http://dx.doi.org/10.1136/bcr-2022-251254
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