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A pilot study of neoadjuvant combination of anti-PD-1 camrelizumab and VEGFR2 inhibitor apatinib for locally advanced resectable oral squamous cell carcinoma

Novel neoadjuvant therapy regimens are warranted for oral squamous cell carcinoma (OSCC). In this phase I trial (NCT04393506), 20 patients with locally advanced resectable OSCC receive three cycles of camrelizumab (200 mg, q2w) and apatinib (250 mg, once daily) before surgery. The primary endpoints...

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Detalles Bibliográficos
Autores principales:	Ju, Wu-tong, Xia, Rong-hui, Zhu, Dong-wang, Dou, Sheng-jin, Zhu, Guo-pei, Dong, Min-jun, Wang, Li-zhen, Sun, Qi, Zhao, Tong-chao, Zhou, Zhi-hang, Liang, Si-yuan, Huang, Ying-ying, Tang, Yong, Wu, Si-cheng, Xia, Jing, Chen, Shi-qing, Bai, Yue-zong, Li, Jiang, Zhu, Qi, Zhong, Lai-ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472189/ https://www.ncbi.nlm.nih.gov/pubmed/36104359 http://dx.doi.org/10.1038/s41467-022-33080-8

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