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Detergent-Free Decellularization of Notochordal Cell-Derived Matrix Yields a Regenerative, Injectable, and Swellable Biomaterial

[Image: see text] Porcine notochordal cell-derived matrix (NCM) has anti-inflammatory and regenerative effects on degenerated intervertebral discs. For its clinical use, safety must be assured. The porcine DNA is concerning because of (1) the transmission of endogenous retroviruses and (2) the infla...

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Detalles Bibliográficos
Autores principales:	Schmitz, Tara C., van Doeselaar, Marina, Tryfonidou, Marianna A., Ito, Keita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472229/ https://www.ncbi.nlm.nih.gov/pubmed/35942885 http://dx.doi.org/10.1021/acsbiomaterials.2c00790

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