Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it

Assessing age‐related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several large‐scale (“omic”) techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcrip...

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Detalles Bibliográficos
Autores principales: Lynch, Cian J, Serrano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
News & Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472234/
https://www.ncbi.nlm.nih.gov/pubmed/36102256
http://dx.doi.org/10.15252/msb.202211276
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author Lynch, Cian J
Serrano, Manuel
author_facet Lynch, Cian J
Serrano, Manuel
author_sort Lynch, Cian J
collection PubMed
description Assessing age‐related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several large‐scale (“omic”) techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcriptional machinery during aging in mice and report some surprising findings.
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spelling pubmed-94722342022-09-21 Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it Lynch, Cian J Serrano, Manuel Mol Syst Biol News & Views Assessing age‐related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several large‐scale (“omic”) techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcriptional machinery during aging in mice and report some surprising findings. John Wiley and Sons Inc. 2022-09-14 /pmc/articles/PMC9472234/ /pubmed/36102256 http://dx.doi.org/10.15252/msb.202211276 Text en © 2022 The Authors. Published under the terms of the CC BY 4.0 license. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle News & Views
Lynch, Cian J
Serrano, Manuel
Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title_full Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title_fullStr Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title_full_unstemmed Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title_short Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title_sort keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472234/
https://www.ncbi.nlm.nih.gov/pubmed/36102256
http://dx.doi.org/10.15252/msb.202211276
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