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Transforming L1000 profiles to RNA-seq-like profiles with deep learning

The L1000 technology, a cost-effective high-throughput transcriptomics technology, has been applied to profile a collection of human cell lines for their gene expression response to > 30,000 chemical and genetic perturbations. In total, there are currently over 3 million available L1000 profiles....

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Detalles Bibliográficos
Autores principales: Jeon, Minji, Xie, Zhuorui, Evangelista, John E., Wojciechowicz, Megan L., Clarke, Daniel J. B., Ma’ayan, Avi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472394/
https://www.ncbi.nlm.nih.gov/pubmed/36100892
http://dx.doi.org/10.1186/s12859-022-04895-5