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Transforming L1000 profiles to RNA-seq-like profiles with deep learning
The L1000 technology, a cost-effective high-throughput transcriptomics technology, has been applied to profile a collection of human cell lines for their gene expression response to > 30,000 chemical and genetic perturbations. In total, there are currently over 3 million available L1000 profiles....
Autores principales: | Jeon, Minji, Xie, Zhuorui, Evangelista, John E., Wojciechowicz, Megan L., Clarke, Daniel J. B., Ma’ayan, Avi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472394/ https://www.ncbi.nlm.nih.gov/pubmed/36100892 http://dx.doi.org/10.1186/s12859-022-04895-5 |
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