Probing spatiotemporal PKA activity at the ryanodine receptor and SERCA2a nanodomains in cardomyocytes

Spatiotemporal regulation of subcellular protein kinase A (PKA) activity for precise substrate phosphorylation is essential for cellular responses to hormonal stimulation. Ryanodine receptor 2 (RyR2) and (sarco)endoplasmic reticulum calcium ATPase 2a (SERCA2a) represent two critical targets of β adr...

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Detalles Bibliográficos
Autores principales: Xu, Bing, Wang, Ying, Bahriz, Sherif M. F. M., Zhao, Meimi, Zhu, Chaoqun, Xiang, Yang K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472443/
https://www.ncbi.nlm.nih.gov/pubmed/36104752
http://dx.doi.org/10.1186/s12964-022-00947-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472443/
https://www.ncbi.nlm.nih.gov/pubmed/36104752
http://dx.doi.org/10.1186/s12964-022-00947-8

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