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Probing spatiotemporal PKA activity at the ryanodine receptor and SERCA2a nanodomains in cardomyocytes

Spatiotemporal regulation of subcellular protein kinase A (PKA) activity for precise substrate phosphorylation is essential for cellular responses to hormonal stimulation. Ryanodine receptor 2 (RyR2) and (sarco)endoplasmic reticulum calcium ATPase 2a (SERCA2a) represent two critical targets of β adr...

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Detalles Bibliográficos
Autores principales:	Xu, Bing, Wang, Ying, Bahriz, Sherif M. F. M., Zhao, Meimi, Zhu, Chaoqun, Xiang, Yang K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472443/ https://www.ncbi.nlm.nih.gov/pubmed/36104752 http://dx.doi.org/10.1186/s12964-022-00947-8

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