Disseminated Tuberculosis Resulting in Septic Shock in an Immunocompetent Patient

Tuberculous infection (TB) is rare in the United Kingdom (UK) with a prevalence rate of 7.3 per 100,000 population in 2020 according to Public Health England. Tuberculous infection of any kind is more common in individuals born in TB-endemic areas. This report describes the case of a male with no si...

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Autores principales: Jaffet, Marjorie F, Abubakar, Mustapha, Ibrahim, Yakub, Ogbuneke, Udoka, Wahoo, Wint
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472472/
https://www.ncbi.nlm.nih.gov/pubmed/36134051
http://dx.doi.org/10.7759/cureus.28025
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author Jaffet, Marjorie F
Abubakar, Mustapha
Ibrahim, Yakub
Ogbuneke, Udoka
Wahoo, Wint
author_facet Jaffet, Marjorie F
Abubakar, Mustapha
Ibrahim, Yakub
Ogbuneke, Udoka
Wahoo, Wint
author_sort Jaffet, Marjorie F
collection PubMed
description Tuberculous infection (TB) is rare in the United Kingdom (UK) with a prevalence rate of 7.3 per 100,000 population in 2020 according to Public Health England. Tuberculous infection of any kind is more common in individuals born in TB-endemic areas. This report describes the case of a male with no significant past medical history who presented with shortness of breath and supraclavicular lymphadenopathy and was subsequently diagnosed with culture-positive disseminated TB. He developed septic shock, underwent treatment and improved. This case highlights an atypical patient profile for the diagnosis of disseminated TB with septic shock and draws attention to the challenges of diagnosing tuberculosis in TB-non-endemic areas. Clinicians should have a high index of suspicion for disseminated tuberculous infection in patients with chronic symptoms and signs affecting multiple organ systems without any obvious cause.
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spelling pubmed-94724722022-09-20 Disseminated Tuberculosis Resulting in Septic Shock in an Immunocompetent Patient Jaffet, Marjorie F Abubakar, Mustapha Ibrahim, Yakub Ogbuneke, Udoka Wahoo, Wint Cureus Internal Medicine Tuberculous infection (TB) is rare in the United Kingdom (UK) with a prevalence rate of 7.3 per 100,000 population in 2020 according to Public Health England. Tuberculous infection of any kind is more common in individuals born in TB-endemic areas. This report describes the case of a male with no significant past medical history who presented with shortness of breath and supraclavicular lymphadenopathy and was subsequently diagnosed with culture-positive disseminated TB. He developed septic shock, underwent treatment and improved. This case highlights an atypical patient profile for the diagnosis of disseminated TB with septic shock and draws attention to the challenges of diagnosing tuberculosis in TB-non-endemic areas. Clinicians should have a high index of suspicion for disseminated tuberculous infection in patients with chronic symptoms and signs affecting multiple organ systems without any obvious cause. Cureus 2022-08-15 /pmc/articles/PMC9472472/ /pubmed/36134051 http://dx.doi.org/10.7759/cureus.28025 Text en Copyright © 2022, Jaffet et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Jaffet, Marjorie F
Abubakar, Mustapha
Ibrahim, Yakub
Ogbuneke, Udoka
Wahoo, Wint
Disseminated Tuberculosis Resulting in Septic Shock in an Immunocompetent Patient
title Disseminated Tuberculosis Resulting in Septic Shock in an Immunocompetent Patient
title_full Disseminated Tuberculosis Resulting in Septic Shock in an Immunocompetent Patient
title_fullStr Disseminated Tuberculosis Resulting in Septic Shock in an Immunocompetent Patient
title_full_unstemmed Disseminated Tuberculosis Resulting in Septic Shock in an Immunocompetent Patient
title_short Disseminated Tuberculosis Resulting in Septic Shock in an Immunocompetent Patient
title_sort disseminated tuberculosis resulting in septic shock in an immunocompetent patient
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472472/
https://www.ncbi.nlm.nih.gov/pubmed/36134051
http://dx.doi.org/10.7759/cureus.28025
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