Cargando…

Variations in Cell Surface ACE2 Levels Alter Direct Binding of SARS-CoV-2 Spike Protein and Viral Infectivity: Implications for Measuring Spike Protein Interactions with Animal ACE2 Orthologs

Mostrar otras versiones (1)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), the most severe pandemic in a century. The virus gains access to host cells when the viral spike protein (S-protein) binds to the host cell surface receptor angiotensin-convert...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kazemi, Soheila, López-Muñoz, Alberto Domingo, Hollý, Jaroslav, Jin, Ling, Yewdell, Jonathan W., Dolan, Brian P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472623/ https://www.ncbi.nlm.nih.gov/pubmed/36000847 http://dx.doi.org/10.1128/jvi.00256-22

Ejemplares similares

Variations in cell-surface ACE2 levels alter direct binding of SARS-CoV-2 Spike protein and viral infectivity: Implications for measuring Spike protein interactions with animal ACE2 orthologs
por: Kazemi, Soheila, et al.
Publicado: (2021)

SARS-CoV-2 and Three Related Coronaviruses Utilize Multiple ACE2 Orthologs and Are Potently Blocked by an Improved ACE2-Ig
por: Li, Yujun, et al.
Publicado: (2020)

V367F Mutation in SARS-CoV-2 Spike RBD Emerging during the Early Transmission Phase Enhances Viral Infectivity through Increased Human ACE2 Receptor Binding Affinity
por: Ou, Junxian, et al.
Publicado: (2021)

A So-Far Overlooked Secondary Conformation State in the Binding Mode of SARS-CoV-2 Spike Protein to Human ACE2 and Its Conversion Rate Are Crucial for Estimating Infectivity Efficacy of the Underlying Virus Variant
por: Sevenich, Marc, et al.
Publicado: (2022)

Characterization of CCoV-HuPn-2018 spike protein-mediated viral entry
por: Liu, Yongmei, et al.
Publicado: (2023)

Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection
por: Ren, Wenlin, et al.
Publicado: (2022)

The “LLQY” Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles
por: Du, Shouwen, et al.
Publicado: (2022)

Isolation of ACE2-dependent and -independent sarbecoviruses from Chinese horseshoe bats
por: Guo, Hua, et al.
Publicado: (2023)

Molecular Basis of Mink ACE2 Binding to SARS-CoV-2 and Its Mink-Derived Variants
por: Su, Chao, et al.
Publicado: (2022)

Highly Efficient SARS-CoV-2 Infection of Human Cardiomyocytes: Spike Protein-Mediated Cell Fusion and Its Inhibition
por: Navaratnarajah, Chanakha K., et al.
Publicado: (2021)

Three Amino Acid Changes in Avian Coronavirus Spike Protein Allow Binding to Kidney Tissue
por: Bouwman, Kim M., et al.
Publicado: (2020)

The PRRA Insert at the S1/S2 Site Modulates Cellular Tropism of SARS-CoV-2 and ACE2 Usage by the Closely Related Bat RaTG13
por: Liu, Shufeng, et al.
Publicado: (2021)

Inhibition of Autophagy Suppresses SARS-CoV-2 Replication and Ameliorates Pneumonia in hACE2 Transgenic Mice and Xenografted Human Lung Tissues
por: Shang, Chao, et al.
Publicado: (2021)

The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release of Infectious Virus
por: Westerbeck, Jason W., et al.
Publicado: (2019)

Spike Glycoprotein and Host Cell Determinants of SARS-CoV-2 Entry and Cytopathic Effects
por: Nguyen, Hanh T., et al.
Publicado: (2021)

The Cellular Characterization of SARS-CoV-2 Spike Protein in Virus-Infected Cells Using the Receptor Binding Domain Binding Specific Human Monoclonal Antibodies
por: Chan, Conrad En-Zuo, et al.
Publicado: (2022)

Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization
por: Kleine-Weber, Hannah, et al.
Publicado: (2019)

N-(4-Hydroxyphenyl) Retinamide Suppresses SARS-CoV-2 Spike Protein-Mediated Cell-Cell Fusion by a Dihydroceramide Δ4-Desaturase 1-Independent Mechanism
por: Hayashi, Yasuhiro, et al.
Publicado: (2021)

SARS-CoV-2 Spike Furin Cleavage Site and S2′ Basic Residues Modulate the Entry Process in a Host Cell-Dependent Manner
por: Lavie, Muriel, et al.
Publicado: (2022)

The Spike-Stabilizing D614G Mutation Interacts with S1/S2 Cleavage Site Mutations To Promote the Infectious Potential of SARS-CoV-2 Variants
por: Gellenoncourt, Stacy, et al.
Publicado: (2022)

SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation
por: Hörnich, Bojan F., et al.
Publicado: (2021)

Biochemical Analysis of Coronavirus Spike Glycoprotein Conformational Intermediates during Membrane Fusion
por: Kawase, Miyuki, et al.
Publicado: (2019)

Host Cellular Protein TRAPPC6AΔ Interacts with Influenza A Virus M2 Protein and Regulates Viral Propagation by Modulating M2 Trafficking
por: Zhu, Pengyang, et al.
Publicado: (2016)

Novel Class of Viral Ankyrin Proteins Targeting the Host E3 Ubiquitin Ligase Cullin-2
por: Odon, Valerie, et al.
Publicado: (2018)

Mutants at the 2-Fold Interface of Adeno-associated Virus Type 2 (AAV2) Structural Proteins Suggest a Role in Viral Transcription for AAV Capsids
por: Aydemir, Fikret, et al.
Publicado: (2016)

Association of Human Papillomavirus 16 E2 with Rad50-Interacting Protein 1 Enhances Viral DNA Replication
por: Campos-León, Karen, et al.
Publicado: (2017)

Cytoplasmic Cargo Receptor p62 Inhibits Avibirnavirus Replication by Mediating Autophagic Degradation of Viral Protein VP2
por: Li, Yahui, et al.
Publicado: (2020)

SARS-CoV-2 nsp5 Exhibits Stronger Catalytic Activity and Interferon Antagonism than Its SARS-CoV Ortholog
por: Chen, Jiyao, et al.
Publicado: (2022)

The M2 proteins of bat influenza A viruses reveal atypical features compared to conventional M2 proteins
por: Thompson, Danielle, et al.
Publicado: (2023)

Glycine 29 Is Critical for Conformational Changes of the Spike Glycoprotein of Mouse Hepatitis Virus A59 Triggered by either Receptor Binding or High pH
por: Mi, Dan, et al.
Publicado: (2019)

Interaction of Nuclear Export Protein with G Protein Pathway Suppressor 2 (GPS2) Facilitates Influenza A Virus Replication by Weakening the Inhibition of GPS2 to RNA Synthesis and Ribonucleoprotein Assembly
por: Gong, Wenxiao, et al.
Publicado: (2021)

Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2
por: Zhao, Xuesen, et al.
Publicado: (2020)

Evidence against the Human Metapneumovirus G, SH, and M2-2 Proteins as Bona Fide Interferon Antagonists
por: Groen, K., et al.
Publicado: (2022)

The Cellular DNA Helicase ChlR1 Regulates Chromatin and Nuclear Matrix Attachment of the Human Papillomavirus 16 E2 Protein and High-Copy-Number Viral Genome Establishment
por: Harris, Leanne, et al.
Publicado: (2016)

Coronavirus Endoribonuclease Ensures Efficient Viral Replication and Prevents Protein Kinase R Activation
por: Zhao, Jing, et al.
Publicado: (2021)

Cytoplasmic Tail Truncation Stabilizes S1-S2 Association and Enhances S Protein Incorporation into SARS-CoV-2 Pseudovirions
por: Zhang, Lizhou, et al.
Publicado: (2023)

Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-Dependent Protein Degradation
por: Westrich, Joseph A., et al.
Publicado: (2018)

SARS-CoV-2 NSP12 Protein Is Not an Interferon-β Antagonist
por: Li, Aixin, et al.
Publicado: (2021)

Mitogen-Activated Protein Kinase Kinase 2, a Novel E2-Interacting Protein, Promotes the Growth of Classical Swine Fever Virus via Attenuation of the JAK-STAT Signaling Pathway
por: Wang, Jinghan, et al.
Publicado: (2016)

Foot-and-mouth disease virus downregulates vacuolar protein sorting 28 to promote viral replication
por: Wang, Xuefei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_l5ae60plj5abqtg3kqj52dhj89