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Type III and Not Type I Interferons Efficiently Prevent the Spread of Rotavirus in Human Intestinal Epithelial Cells

Rotavirus infects intestinal epithelial cells and is the leading cause of gastroenteritis in infants worldwide. Upon viral infection, intestinal cells produce type I and type III interferons (IFNs) to alert the tissue and promote an antiviral state. These two types of IFN bind to different receptors...

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Detalles Bibliográficos
Autores principales: Doldan, Patricio, Dai, Jin, Metz-Zumaran, Camila, Patton, John T., Stanifer, Megan L., Boulant, Steeve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472630/
https://www.ncbi.nlm.nih.gov/pubmed/36000839
http://dx.doi.org/10.1128/jvi.00706-22