A counterintuitive antibody cocktail disrupts coxsackievirus

Utilizing monoclonal antibodies to prevent and treat infectious diseases has been accelerated by the COVID-19 pandemic. In this issue of Cell Host & Microbe, Zheng et al. show how a three-monoclonal-antibody cocktail, that defies conventions of “rational design” for a therapeutic agent, function...

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Detalles Bibliográficos
Autores principales: Zost, Seth J., Vogt, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472682/
https://www.ncbi.nlm.nih.gov/pubmed/36108609
http://dx.doi.org/10.1016/j.chom.2022.08.010
Descripción
Sumario:Utilizing monoclonal antibodies to prevent and treat infectious diseases has been accelerated by the COVID-19 pandemic. In this issue of Cell Host & Microbe, Zheng et al. show how a three-monoclonal-antibody cocktail, that defies conventions of “rational design” for a therapeutic agent, functions cooperatively to disrupt coxsackievirus virions.

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