Structural and functional characterisation of a stable, broad-specificity multimeric sialidase from the oral pathogen Tannerella forsythia

Sialidases are glycosyl hydrolase enzymes targeting the glycosidic bond between terminal sialic acids and underlying sugars. The NanH sialidase of Tannerella forsythia, one of the bacteria associated with severe periodontal disease plays a role in virulence. Here, we show that this broad-specificity...

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Detalles Bibliográficos
Autores principales: Satur, Marianne J., Urbanowicz, Paulina A., Spencer, Daniel I. R., Rafferty, John, Stafford, Graham P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472817/
https://www.ncbi.nlm.nih.gov/pubmed/35916484
http://dx.doi.org/10.1042/BCJ20220244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472817/
https://www.ncbi.nlm.nih.gov/pubmed/35916484
http://dx.doi.org/10.1042/BCJ20220244

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