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Development of E-ice-COLD-PCR assay combined with HRM analysis for Nucleophosmin1 gene mutation detection in acute myelogenous leukemia

Mutations of the nucleophosmin1 (NPM1) gene represent the most frequent molecular alteration in acute myelogenous leukemia (AML), especially in patients with AML who have a normal karyotype. These alterations have been shown to carry favorable prognostic significance in patients with AML. Several me...

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Detalles Bibliográficos
Autores principales: Kongta, Rattana, Panyasit, Noppamas, Jansaento, Wuttichote, Duangmano, Suwit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473412/
https://www.ncbi.nlm.nih.gov/pubmed/36103476
http://dx.doi.org/10.1371/journal.pone.0274034