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SARS-CoV-2 takes the bait: Exosomes as endogenous decoys

Writing in PLOS Biology, Ching and colleagues show that ACE2-decorated exosomes are deployed as natural inhibitory decoys against SARS-CoV-2. High decoy levels correlate with improved patient outcomes, suggesting they directly help COVID-19 recovery and supporting the concept of successful future de...

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Detalles Bibliográficos
Autores principales: Fernbach, Sonja, Hale, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473416/
https://www.ncbi.nlm.nih.gov/pubmed/36103486
http://dx.doi.org/10.1371/journal.pbio.3001787
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author Fernbach, Sonja
Hale, Benjamin G.
author_facet Fernbach, Sonja
Hale, Benjamin G.
author_sort Fernbach, Sonja
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description Writing in PLOS Biology, Ching and colleagues show that ACE2-decorated exosomes are deployed as natural inhibitory decoys against SARS-CoV-2. High decoy levels correlate with improved patient outcomes, suggesting they directly help COVID-19 recovery and supporting the concept of successful future decoy-based therapies.
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spelling pubmed-94734162022-09-15 SARS-CoV-2 takes the bait: Exosomes as endogenous decoys Fernbach, Sonja Hale, Benjamin G. PLoS Biol Primer Writing in PLOS Biology, Ching and colleagues show that ACE2-decorated exosomes are deployed as natural inhibitory decoys against SARS-CoV-2. High decoy levels correlate with improved patient outcomes, suggesting they directly help COVID-19 recovery and supporting the concept of successful future decoy-based therapies. Public Library of Science 2022-09-14 /pmc/articles/PMC9473416/ /pubmed/36103486 http://dx.doi.org/10.1371/journal.pbio.3001787 Text en © 2022 Fernbach, Hale https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Primer
Fernbach, Sonja
Hale, Benjamin G.
SARS-CoV-2 takes the bait: Exosomes as endogenous decoys
title SARS-CoV-2 takes the bait: Exosomes as endogenous decoys
title_full SARS-CoV-2 takes the bait: Exosomes as endogenous decoys
title_fullStr SARS-CoV-2 takes the bait: Exosomes as endogenous decoys
title_full_unstemmed SARS-CoV-2 takes the bait: Exosomes as endogenous decoys
title_short SARS-CoV-2 takes the bait: Exosomes as endogenous decoys
title_sort sars-cov-2 takes the bait: exosomes as endogenous decoys
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473416/
https://www.ncbi.nlm.nih.gov/pubmed/36103486
http://dx.doi.org/10.1371/journal.pbio.3001787
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