Knockout of Trpa1 accelerates age-related cardiac fibrosis and dysfunction

Age-related cardiac fibrosis contributes to the development of heart failure with preserved ejection fraction which lacks ideal treatment. Transient receptor potential ankyrin 1 (TRPA1) is an oxidative stress sensor and could attenuate age-related pathologies in invertebrates. The present study aime...

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Detalles Bibliográficos
Autores principales: Ma, Shuangtao, Wang, Donna H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473441/
https://www.ncbi.nlm.nih.gov/pubmed/36103570
http://dx.doi.org/10.1371/journal.pone.0274618