Knockout of Trpa1 accelerates age-related cardiac fibrosis and dysfunction
Age-related cardiac fibrosis contributes to the development of heart failure with preserved ejection fraction which lacks ideal treatment. Transient receptor potential ankyrin 1 (TRPA1) is an oxidative stress sensor and could attenuate age-related pathologies in invertebrates. The present study aime...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473441/ https://www.ncbi.nlm.nih.gov/pubmed/36103570 http://dx.doi.org/10.1371/journal.pone.0274618 |