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Targeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells

Spleen tyrosine kinase (Syk) expression have been both positively and negatively associated with tumorigenesis. Our goal was to evaluate the contribution of Syk and its two splice variants, full length Syk (L) and short isoform Syk (S), in the tumor biology of colorectal cancer cells (CRC). The anal...

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Detalles Bibliográficos
Autores principales:	Denis, Vincent, Cassagnard, Nadège, Del Rio, Maguy, Cornillot, Emmanuel, Bec, Nicole, Larroque, Christian, Jeanson, Laura, Jarlier, Marta, Combès, Eve, Robert, Bruno, Gongora, Céline, Martineau, Pierre, Dariavach, Piona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473616/ https://www.ncbi.nlm.nih.gov/pubmed/36103569 http://dx.doi.org/10.1371/journal.pone.0274390

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