The PTPIP51 coiled-coil domain is important in VAPB binding, formation of ER-mitochondria contacts and IP3 receptor delivery of Ca(2+) to mitochondria

Signaling between the endoplasmic reticulum (ER) and mitochondria regulates a number of fundamental physiological processes. This signaling involves close physical contacts between the two organelles that are mediated by the VAPB-PTPIP51 ″tethering” proteins. The VAPB-PTPIP51 tethers facilitate inos...

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Detalles Bibliográficos
Autores principales: Mórotz, Gábor M., Martín-Guerrero, Sandra M., Markovinovic, Andrea, Paillusson, Sebastien, Russell, Matthew R. G., Machado, Pedro M. Pereira, Fleck, Roland A., Noble, Wendy, Miller, Christopher C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473665/
https://www.ncbi.nlm.nih.gov/pubmed/36120587
http://dx.doi.org/10.3389/fcell.2022.920947

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