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Remote Supratentorial Recurrent Medulloblastoma: Case Study and Literature Review
Medulloblastomas comprise 10% of pediatric brain tumors. Subfrontal recurrence is uncommon and has been associated with prone positioning, inadequate irradiation of the cribriform plate area, and hydrocephalus management. We discuss the case report of an 8-year-old boy with subfrontal medulloblastom...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473848/ https://www.ncbi.nlm.nih.gov/pubmed/36120640 http://dx.doi.org/10.1055/s-0042-1750389 |
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author | Dominari, Asimina Antoniades, Elias Capiccelo, Antonio Hatzipantelis, Emmanuil Foroglou, Nikolaos |
author_facet | Dominari, Asimina Antoniades, Elias Capiccelo, Antonio Hatzipantelis, Emmanuil Foroglou, Nikolaos |
author_sort | Dominari, Asimina |
collection | PubMed |
description | Medulloblastomas comprise 10% of pediatric brain tumors. Subfrontal recurrence is uncommon and has been associated with prone positioning, inadequate irradiation of the cribriform plate area, and hydrocephalus management. We discuss the case report of an 8-year-old boy with subfrontal medulloblastoma recurrence. The literature was reviewed using terms such as “medulloblastoma,” “subfrontal recurrence,” and “child.” Forty-eight cases of subfrontal medulloblastoma recurrence were identified. The mean age at presentation was 12.3 years. Gross total resection was achieved in 44%, most patients received adjuvant radiation therapy, and approximately 25% received chemotherapy. The mean recurrence interval was 2.6 years. The mean number of recurrences per patient was 1.2 and the mean survival period was 3.3 years. Even in the case of meticulous resection and sufficient irradiation, recurrences may still occur. Our case indicates that resection of the recurrent lesion and repeat irradiation may benefit patients with satisfactory short-term results. |
format | Online Article Text |
id | pubmed-9473848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94738482022-09-15 Remote Supratentorial Recurrent Medulloblastoma: Case Study and Literature Review Dominari, Asimina Antoniades, Elias Capiccelo, Antonio Hatzipantelis, Emmanuil Foroglou, Nikolaos Asian J Neurosurg Medulloblastomas comprise 10% of pediatric brain tumors. Subfrontal recurrence is uncommon and has been associated with prone positioning, inadequate irradiation of the cribriform plate area, and hydrocephalus management. We discuss the case report of an 8-year-old boy with subfrontal medulloblastoma recurrence. The literature was reviewed using terms such as “medulloblastoma,” “subfrontal recurrence,” and “child.” Forty-eight cases of subfrontal medulloblastoma recurrence were identified. The mean age at presentation was 12.3 years. Gross total resection was achieved in 44%, most patients received adjuvant radiation therapy, and approximately 25% received chemotherapy. The mean recurrence interval was 2.6 years. The mean number of recurrences per patient was 1.2 and the mean survival period was 3.3 years. Even in the case of meticulous resection and sufficient irradiation, recurrences may still occur. Our case indicates that resection of the recurrent lesion and repeat irradiation may benefit patients with satisfactory short-term results. Thieme Medical and Scientific Publishers Pvt. Ltd. 2022-08-24 /pmc/articles/PMC9473848/ /pubmed/36120640 http://dx.doi.org/10.1055/s-0042-1750389 Text en Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Dominari, Asimina Antoniades, Elias Capiccelo, Antonio Hatzipantelis, Emmanuil Foroglou, Nikolaos Remote Supratentorial Recurrent Medulloblastoma: Case Study and Literature Review |
title | Remote Supratentorial Recurrent Medulloblastoma: Case Study and Literature Review |
title_full | Remote Supratentorial Recurrent Medulloblastoma: Case Study and Literature Review |
title_fullStr | Remote Supratentorial Recurrent Medulloblastoma: Case Study and Literature Review |
title_full_unstemmed | Remote Supratentorial Recurrent Medulloblastoma: Case Study and Literature Review |
title_short | Remote Supratentorial Recurrent Medulloblastoma: Case Study and Literature Review |
title_sort | remote supratentorial recurrent medulloblastoma: case study and literature review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473848/ https://www.ncbi.nlm.nih.gov/pubmed/36120640 http://dx.doi.org/10.1055/s-0042-1750389 |
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