Cargando…

MicroRNA-1306-5p Regulates the METTL14-Guided m6A Methylation to Repress Acute Myeloid Leukemia

miRNA and m6A methylation are two key regulators in cancers. However, in acute myeloid leukemia (AML), the relationship of miRNA and m6A methylation remains unclear. The present work is aimed at determining the effect of m6A methylation induced by miRNAs on AML and its underlying mechanism. The expr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jiajia, Wu, Yanping, Wang, Meng, Chen, Xiaofeng, Li, Zhongyu, Bai, Xue, Wu, Haotian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9473907/ https://www.ncbi.nlm.nih.gov/pubmed/36118827 http://dx.doi.org/10.1155/2022/5787808

Ejemplares similares

LncRNA UCA1 Promotes the Progression of AML by Upregulating the Expression of CXCR4 and CYP1B1 by Affecting the Stability of METTL14
por: Li, Jiajia, et al.
Publicado: (2022)

The m(6)A RNA methyltransferase METTL3/METTL14 promotes leukemogenesis through the mdm2/p53 pathway in acute myeloid leukemia
por: Sang, Lina, et al.
Publicado: (2022)

Targeting METTL14 and RNA methylation to treat osteosarcoma
por: Ren, Lili, et al.
Publicado: (2022)

Eltrombopag as an Allosteric Inhibitor of the METTL3-14 Complex Affecting the m(6)A Methylation of RNA in Acute Myeloid Leukemia Cells
por: Lee, Je-Heon, et al.
Publicado: (2022)

HIV Replication Is Increased by RNA Methylation METTL3/METTL14/WTAP Complex Activators
por: Selberg, Simona, et al.
Publicado: (2021)

Analysis of METTL3 and METTL14 in hepatocellular carcinoma
por: Liu, Xiangxiang, et al.
Publicado: (2020)

METTL14-mediated RNA methylation in digestive system tumors
por: Hu, Jiexuan, et al.
Publicado: (2023)

A METTL3-METTL14 complex mediates mammalian nuclear RNA N(6)-adenosine methylation
por: Liu, Jianzhao, et al.
Publicado: (2013)

RNA binding to human METTL3-METTL14 restricts N(6)-deoxyadenosine methylation of DNA in vitro
por: Qi, Shan, et al.
Publicado: (2022)

The Distinct Function and Localization of METTL3/METTL14 and METTL16 Enzymes in Cardiomyocytes
por: Arcidiacono, Orazio Angelo, et al.
Publicado: (2020)

The study of METTL3 and METTL14 expressions in childhood ETV6/RUNX1‐positive acute lymphoblastic leukemia
por: Sun, Congcong, et al.
Publicado: (2019)

PRMT1 methylates METTL14 to modulate its oncogenic function
por: Wang, Jingchao, et al.
Publicado: (2023)

The first true millipede—1306 legs long
por: Marek, Paul E., et al.
Publicado: (2021)

Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases
por: Xu, Yeqiu, et al.
Publicado: (2023)

Roles of the m6A methyltransferases METTL3, METTL14, and WTAP in pulmonary tuberculosis
por: Zhang, Tian-Ping, et al.
Publicado: (2022)

Correction: Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases
por: Xu, Yeqiu, et al.
Publicado: (2023)

Insights into roles of METTL14 in tumors
por: Liu, Xin, et al.
Publicado: (2021)

Novel prognostic biomarkers, METTL14 and YTHDF2, associated with RNA methylation in Ewing’s sarcoma
por: Jiang, Jie, et al.
Publicado: (2022)

Role of MMP-2 (-1306 C/T) Polymorphism in Pituitary Adenoma
por: Glebauskiene, Brigita, et al.
Publicado: (2016)

Curdione induces ferroptosis mediated by m6A methylation via METTL14 and YTHDF2 in colorectal cancer
por: Wang, Fang, et al.
Publicado: (2023)

Biochemical and transcriptomic analyses of drought stress responses of LY1306 tobacco strain
por: Yang, Huijuan, et al.
Publicado: (2017)

The Comprehensive Analysis of N6-Methyadenosine Writer METTL3 and METTL14 in Gastric Cancer
por: Ge, Yiling, et al.
Publicado: (2023)

Knockdown of METTL14 inhibits the growth and invasion of cervical cancer
por: Geng, Feng, et al.
Publicado: (2019)

METTL3 affects FLT3-ITD+ acute myeloid leukemia by mediating autophagy by regulating PSMA3-AS1 stability
por: Wu, Shenghao, et al.
Publicado: (2023)

SEDT2/METTL14-mediated m6A methylation awakening contributes to hypoxia-induced pulmonary arterial hypertension in mice
por: Zhou, Xue-Liang, et al.
Publicado: (2021)

UP1306, a Botanical Composition with Analgesic and Anti-inflammatory Effect
por: Yimam, Mesfin, et al.
Publicado: (2016)

The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis
por: Kobayashi, Masatoshi, et al.
Publicado: (2018)

Interactions, localization, and phosphorylation of the m(6)A generating METTL3–METTL14–WTAP complex
por: Schöller, Eva, et al.
Publicado: (2018)

Solution structure of the RNA recognition domain of METTL3-METTL14 N(6)-methyladenosine methyltransferase
por: Huang, Jinbo, et al.
Publicado: (2018)

A cryptic pocket in METTL3-METTL14 regulates m(6)A conversion and sensing
por: Qi, Shan, et al.
Publicado: (2023)

Tumor-suppressive MEG3 induces microRNA-493-5p expression to reduce arabinocytosine chemoresistance of acute myeloid leukemia cells by downregulating the METTL3/MYC axis
por: Wang, Airong, et al.
Publicado: (2022)

WTAP–VIRMA counteracts dsDNA binding of the m(6)A writer METTL3–METTL14 complex and maintains N(6)-adenosine methylation activity
por: Yan, Xuhui, et al.
Publicado: (2023)

New insight into the catalytic -dependent and -independent roles of METTL3 in sustaining aberrant translation in chronic myeloid leukemia
por: Ianniello, Zaira, et al.
Publicado: (2021)

Nomogram to predict the prognosis of parotid gland mucoepidermoid carcinoma: a population-based study of 1306 cases
por: Sun, Jian, et al.
Publicado: (2019)

DDX5/METTL3-METTL14/YTHDF2 Axis Regulates Replication of Influenza A Virus
por: Zhao, Lingcai, et al.
Publicado: (2022)

m(6)A independent genome-wide METTL3 and METTL14 redistribution drives senescence-associated secretory phenotype
por: Liu, Pingyu, et al.
Publicado: (2021)

METTL14 suppresses pyroptosis and diabetic cardiomyopathy by downregulating TINCR lncRNA
por: Meng, Liping, et al.
Publicado: (2022)

CircAXL Knockdown Alleviates Aβ(1-42)-Induced Neurotoxicity in Alzheimer’s Disease via Repressing PDE4A by Releasing miR-1306-5p
por: Meng, Shengxi, et al.
Publicado: (2022)

Mettl14-driven senescence-associated secretory phenotype facilitates somatic cell reprogramming
por: Xi, Chenxiang, et al.
Publicado: (2022)

Genetic Variants in METTL14 are Associated with the Risk of Acute Lymphoblastic Leukemia in Southern Chinese Children: A Five-Center Case-Control Study
por: Luo, Ailing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fli8bh6ltfgn31skta0hhn1atl