CTCF DNA-binding domain undergoes dynamic and selective protein–protein interactions

CTCF is a predominant insulator protein required for three-dimensional chromatin organization. However, the roles of its insulation of enhancers in a 3D nuclear organization have not been fully explained. Here, we found that the CTCF DNA-binding domain (DBD) forms dynamic self-interacting clusters....

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Detalles Bibliográficos
Autores principales: Zhou, Rong, Tian, Kai, Huang, Jie, Duan, Wenjia, Fu, Hongye, Feng, Ying, Wang, Hui, Jiang, Yongpeng, Li, Yuanjun, Wang, Rui, Hu, Jiazhi, Ma, Hanhui, Qi, Zhi, Ji, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474293/
https://www.ncbi.nlm.nih.gov/pubmed/36117989
http://dx.doi.org/10.1016/j.isci.2022.105011

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